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Identification and functional expression of olfactory receptors specific for key food alkylpyrazines


, : Identification and functional expression of olfactory receptors specific for key food alkylpyrazines. Flavour Research at the Dawn of the Twenty first Century Proceedings of the 10th Weurman Flavour Research Symposium, Beaune, France, 25-28 June, 2002: 269-274

Members of the large group of alkylpyrazines are considered to be key food odourants in raw and heated food. Using a fluorescence imaging plate reader system, we screened 96 mouse olfactory receptor chimaeras expressed in a human cell line for intracellular calcium signals by application of the key food odourant 2,3-diethyl-5-methylpyrazine. We identified one responding receptor.

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