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Antifungal activities of essential oils from Glehnia littoralis alone and in combination with ketoconazole

, : Antifungal activities of essential oils from Glehnia littoralis alone and in combination with ketoconazole. Natural Product Sciences 11(2): 92-96

The antifungal activities of essential oils from the leaves of Glehnia littoralis, cultivated in Korea, were evaluated against Trichophyton rubrum by broth dilution and disk diffusion tests. Additionally, the effects of the oils together with ketoconazole were tested by the checkerboard titre test. The essential oil fraction and its main components showed significant inhibition of the tested T. rubrum, with low inhibitory concentrations (MICs) ranging from 16 to 32 mg/ml.


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