+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Arabidopsis kinome: after the casting

, : Arabidopsis kinome: after the casting. Functional & Integrative Genomics 4(3): 163-187

Arabidopsis thaliana is used as a favourite experimental organism for many aspects of plant biology. We capitalized on the recently available Arabidopsis genome sequence and predicted proteome, to draw up a genome-scale protein serine/threonine kinase (PSTK) inventory. The PSTKs represent about 4% of the A. thaliana proteome. In this study, we provide a description of the content and diversity of the non-receptor PSTKs. These kinases have crucial functions in sensing, mediating and coordinating cellular responses to an extensive range of stimuli. A total of 369 predicted non receptor PSTKs were detailed: the Raf superfamily, the CMGC, CaMK, AGC and STE families, as well as a few small clades and orphan sequences. An extensive relationship analysis of these kinases allows us to classify the proteins in superfamilies, families, sub-families and groups. The classification provides a better knowledge of the characteristics shared by the different clades. We focused on the MAP kinase module elements, with particular attention to their docking sites for protein-protein interaction and their biological function. The large number of A. thaliana genes encoding kinases might have been achieved through successive rounds of gene and genome duplications. The evolution towards an increasing gene number suggests that functional redundancy plays an important role in plant genetic robustness.


PMID: 14740254

DOI: 10.1007/s10142-003-0096-4

Other references

Michel, P.; Rérat, A., 1998: Effect of adding sugar beet fibre and wheat bran to a starch diet on the absorption kinetics of glucose, amino-nitrogen and volatile fatty acids in the pig. The purpose of this study with the pig was to analyse the influence of the type of dietary fibre on quantitative kinetics of the absorption of nutrients deriving from enzymatic digestion in the small intestine and that of volatile fatty acids (VFA...

Jampel, R.S., 1966: The action of the superior oblique muscle. An experimental study in the monkey. Archives of Ophthalmology 75(4): 535-544

Gilliam F.R.; May J.V., 1981: Mono layer growth and differentiated function in granulosa cells cultured after freezing. Biology of Reproduction 24(SUPPL 1): 86A

Postweiler, K.; Hartmann, W.; Stosser, R., 1990: The development of sphaeroblasts, burr knots and adventitious buds in fruit trees. Trees of various apple and pear cultivars in budwood gardens were examined morphologically and histologically at different times of the year during 1984-86. Severe pruning caused the development of sphaeroblasts, burr knots and adventitious buds....

Lukaszewska, Irena, 1992: Scopolamine impairs response-to-change based on weak memory trace. Acta Neurobiologiae Experimentalis (Warsaw) 52(3): 187

Muzj E., 1988: Biometry in the diagnosis and classification of orofacial malformations. The biometrical account of oral and facial orthopedics requires a biological conception of dentofacial anomalies. The diagnosis and classification cannot be based on the way they manifest. More important are the pathological causes together with t...

Walsh Gregory J.; Aleinikoff John N., 1999: U-Pb zircon age of metafelsite from the Pinney Hollow Formation; implications for the development of the Vermont Appalachians. The Pinney Hollow Formation of central Vermont is part of a rift-clastic to drift-stage sequence of cover rocks deposited on the Laurentian margin during the development of the Iapetan passive margin in Late Proterozoic to Cambrian time. Conventio...

Dowdeswell, W.H., 1956: Isolation and adaptation in populations of the Lepidoptera. Proceedings of the Royal Society London Ser B: 145: 322-329

McAuley, D.F.; McGurk, C.; Nugent, A.G.; Hanratty, C.; Hayes, J.R.; Johnston, G.D., 2000: Vasoconstriction to endothelin-1 is blunted in non-insulin-dependent diabetes: a dose-response study. The haemodynamic hypothesis for the pathogenesis of diabetic microangiopathy argues that an initial increase in microvascular blood flow leads to microvascular sclerosis and disturbed autoregulation. Endothelin-1 (ET-1) is an endothelium-derived v...

Bernacka, H., 2006: Cytological quality of goat milk on the basis of the somatic cell count. The aim of the present paper was to evaluate the cytological quality of goat milk based on the somatic cell count in the respective months of lactation. The effect of somatic cell count on the milk production and chemical composition of milk was a...