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Crystal structure of the 28 kDa glutathione S-transferase from Schistosoma haematobium

, : Crystal structure of the 28 kDa glutathione S-transferase from Schistosoma haematobium. Biochemistry 42(34): 10084-10094

Schistomiasis is a debilitating parasitic disease which affects 200 million people, causing life-threatening complications in 10% of the patients. This paper reports the crystal structure of the Schistosoma haematobium 28 kDa glutathione S-transferase, a multifunctional enzyme involved in host-parasite interactions and presently considered as a promising vaccine candidate against schistosomiasis.


PMID: 12939136

DOI: 10.1021/bi034449r

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