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High-lysine corn produced by the combination of enhanced lysine biosynthesis and reduced zein accumulation


, : High-lysine corn produced by the combination of enhanced lysine biosynthesis and reduced zein accumulation. Plant Biotechnology Journal 3(6): 555-569

Corn is one of the major crops in the world, but its low lysine content is often problematic for animal consumption. While exogenous lysine supplementation is still the most common solution for today's feed corn, high-lysine corn has been developed through genetic research and biotechnology. Reducing the lysine-poor seed storage proteins, zeins, or expressing a deregulated lysine biosynthetic enzyme, CordapA, has shown increased total lysine or free lysine content in the grains of modified corn plants, respectively. Here, by combining these two approaches through genetic crosses, the total lysine content has more than doubled in F1 progeny. We also observe a synergy between the transgenic zein reduction and the enhanced lysine biosynthesis by CordapA expression. The zein reduction plants are found to accumulate higher levels of aspartate, asparagine and glutamate, and therefore, provide excess precursors for the enhanced lysine biosynthesis.

US$19.90

PMID: 17147627

DOI: 10.1111/j.1467-7652.2005.00146.x


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Szumiel, I.; Walicka, M., 1980: Cytotoxicity and the effect of combined treatment with X-rays of an anticancer 1-nitro-9-aminoacridine derivative in L5178Y-R and L5178Y-S cells. The response to nitracrine, 1-nitro-9-[3'(N,N-dimethyl)aminopropyl] aminoacridine, an anticancer agent, was examined in two strains of murine lymphoma L5178Y inversely cross-sensitive to X-rays and UV light. A marked difference was found in s...

Dewan, R.; Dewan, A.; Hare, S.; Bhardwaj, M.; Mehrotra, K., 2017: Diagnostic Performance of Serum Human Epididymis Protein 4 in Endometrial Carcinoma: A Pilot Study. Endometrial Cancer (EC) is a common female malignant disorder. To date, there are no specific tumour markers for EC that may be routinely used in clinical practice for diagnosis. To evaluate the diagnostic performance of the serum Human Epididymis...

Maier, V.; Yokoyama, H., 1974: Vitamin induction in fruits and vegetables with bioregulators. Nutritional Qualities of Fresh Fruits and Vegetablesp L White and N Selvey eds: 77-180

Zheng, J.; Li, P.; Ma, S.; Geng, M., 2013: Epithelioid hemangioendothelioma of the meninges mimicking metastatic carcinoma: a case report. Epithelioid hemangioendothelioma (EHE) is a rare, locally aggressive well-differentiated endothelial tumor, which frequently develops from the peripheral veins. Meningeal EHE has only been reported in four previous cases. Here we report the case o...

Flascher, I.; Shaw, R., E.; Michaels, C., F.; Flascher, O., M., 2006: A primer on the use of intentional dynamics measures and methods in applied research. Intentional dynamics is a modeling framework that provides methods and measures with which to evaluate and predict goal-directed behavior. The authors introduce the framework by showing how it can be used to solve two general problems in the desi...

Decarvalho, S., 1963: Effect of RNA from normal human bone marrow on leukaemic marrow in vivo. Nature 197: 1077-1080

Rachini, A.; Pietrella, D.; Lupo, P.; Torosantucci, A.; Chiani, P.; Bromuro, C.; Proietti, C.; Bistoni, F.; Cassone, A.; Vecchiarelli, A., 2007: An anti-beta-glucan monoclonal antibody inhibits growth and capsule formation of Cryptococcus neoformans in vitro and exerts therapeutic, anticryptococcal activity in vivo. In this study we tested the in vitro and in vivo anti-Cryptococcus neoformans activity of an antilaminarin (anti-beta-glucan) monoclonal antibody (MAb 2G8) (immunoglobulin G2b) which was previously shown to inhibit the growth of beta-glucan-exposi...

Konstantinovskiy A.A., 1999: Potential gold ore-bearing platforms of quartz-sand formations. Rudy i Metally 1999(1): 54-55

Granick, J.; Cambron, J.A.; Gupta, D.; Aslam, A.; Wodek, T.; Grutsch, J.F.; Lis, C.G., 2016: Self -Reported Quality of Life in users and non-users of dietary supplements in cancer. NlmCategory="UNASSIGNED">8232 Background: Hospital-based surveys suggest that cancer patients routinely use dietary supplements, which include vitamins, minerals, and herbs. We described the QoL characteristics of users of dietary sup...

Metheny, N.A.; Smith, L.; Stewart, B.J., 2000: Development of a reliable and valid bedside test for bilirubin and its utility for improving prediction of feeding tube location. The addition of laboratory bilirubin readings to an algorithm based on pH alone improves prediction of feeding tube location; although reliable pH-teststrips are available, there is no bedside test to measure bilirubin in feeding tube aspirates. T...