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Paraquat induces apoptosis of cultured rat cortical cells

, : Paraquat induces apoptosis of cultured rat cortical cells. Molecules and Cells 17(1): 102-107

Paraquat (PQ; 1,1'-dimethyl-4,4'-bipyridinium dichloride) is widely used as a universal herbicide. Although systemic treatment with PQ gives rise to the highest level of the herbicide in the cerebral cortex, our knowledge of its effects in this brain region is very limited. We took advantage of rat cortical cell cultures to analyze how PQ affects cortical neurons.


PMID: 15055535

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