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A study of labeled pluronic f 68 poly oxalkal after intra venous injection into the dog

, : A study of labeled pluronic f 68 poly oxalkal after intra venous injection into the dog. Journal of Surgical Research 25(4): 349-356

3H-Labeled Pluronic F-68 [polyoxalkal] was given i.v. to dogs. The 3H-labeled Pluronic F-68 was measured in whole blood, plasma, plasma protein-free filtrate, washed and unwashed red blood cells, urine and lymph during the 25-h administration and in various organs at the end of 24 h. Approximately 75% of the detergent was transported in the plasma as free Pluronic F-68, and 25% appeared to be attached to albumin. At the end of 24 h, approximately 40% of the initial dose was excreted in the urine, and 3H-labeled Pluronic was found in all organs. Pluronic F-68 (polyoxalkal), a nonionic surface-active agent, has been used as a detergent for a variety of biological purposes including the stabilization of fat emulsions, reduction of blood viscosity, diminution of platelet adhesiveness [10, 2], and as a perfusion additive for extracorporeal circulation.


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Cruces Blanco, C.; Segura Carretero, A.; Galvez Mata, L.; Fernandez Gutierrez, A., 2001: Simultaneous determination, by capillary zone electrophoresis, of multiple components of different industrial products. Four parabens (esters of 4-hydroxybenzoic acid), effective preservatives against the growth of bacteria, yeast, and mold in numerous industrial products, have been used in this work as model compounds to demonstrate the resolving power of capillar...

Lim L.M.; Strobel R.J.; Daubenspeck J.A., 1992: Early cortical evoked potentials ceps arising from pressure pulses applied to the human upper airway. FASEB Journal 6(5): A1758

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Koshima I.; Endoh T., 1988: Experimental study of free and vascularized muscle grafts multifactorial analyses on muscle generation of transplanted muscles. A comparative study on muscle generation in both free and vascularized muscle grafts has been carried out utilizing the rat gastrocnemius muscle. Free and vascularized muscle grafts harvested from the gluteal region and transplanted orthotopically...

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Daniel, R., 1955: Alcoholism and the private practitioner. Journal - Michigan State Medical Society 54(7): 820-1; Passim

Miller, D.L., 1975: Ethanol fermentation and potential. A review of alcohol production processes, including a discussion of wood (cellulosic) fermentation.

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