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Absence of atpase activity in the avian leukosis virus strain e 26


, : Absence of atpase activity in the avian leukosis virus strain e 26. Obshta i Sravnitelna Patologiya 16: 23-28

The avian leukosis virus strain E-26 was isolated in Bulgaria by Ibahob et al. (1962). It was determined as erythroblastosis virus on the basis of the haematologic and histopathologic characteristics. The results of some in vitro experiments carried out with this virus in certain other laboratories founded the proposal strain E-26 to be reclassified as a myeloblastosis virus. As the avian myeloblastosis virus strain BAI-A possessed high adenosinetriphosphatase activity, experiments were carried out to examine whether strain E-26 manifested such an activity, too. The virus was obtained from plasma of White Leghorn chickens Line 15I positively responded to strain E-26. The enzyme activity was determined after the method of Beaudreau and Becker (1958). No adenosinetriphosphatase activity was established in any of the 17 plasma samples of chickens with acute leukosis induced by virus strain E-26 while it was sufficiently high in all plasma samples of chickens with myeloblastosis induced by the avian myeloblastosis virus. Adenosinetriphosphatase activity was not detected even after 50-fold concentration of plasma samples of chickens responded positively to strain E-26. A conclusion was drawn that the avian leukosis strain E-26 differed from the avian myeloblastosis virus strain BAI-A in respect of its adenosinetriphosphatase activity.

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