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Althesin in high risk patients with heart disease in orthopedic surgery


, : Althesin in high risk patients with heart disease in orthopedic surgery. International Journal of Clinical Pharmacology, Therapy, and Toxicology 23(7): 284-290

Althesin was used in 65 patients with heart diseases undergoing orthopedic surgery, alone or in association with neuroleptanalgesic drugs. Patients were classified according to four types of heart diseases: atrial fibrillation in older patients (41.53%), disorders of cardiac rhythm (23.07%), valvular diseases (9.23%), ischemic heart disease (26.15%) and according to the degree of risk (ASA 3 and 4). All patients were carefully studied before the operation, and adequately treated with cardiac drugs in order to reduce heart rate, to reduce blood pressure and to reduce heart failure, whenever necessary. Anesthesia was induced with Althesin in all patients, and maintained with Althesin/N2O/O2 in 24.61% of the cases, and Althesin/N2O/O2/NLA in 75.39% of the cases. No significant changes in heart rate or in blood pressure were observed either during surgery or in the first 24 hours after the operation. There were five deaths in the days after the operation, one of which was due to surgery. One patient was discharged while still in a coma. All the other patients were discharged from the hospital within approximately four weeks from the day of the operation in good general condition. It was concluded that Althesin is a very reliable anesthetic agent for patients with heart diseases.

US$29.90

PMID: 4030159


Other references

Dumitrescu, I.P.tcu, D.M.asnicov, I.T.dorascu, R.S.oica, A.I.nescu, F.B.rbu, M., 1978: Study on the improvement of sperm production in rams. Lucrari stiintifice Seria D Zootehnie76 (pub 1978) 18(18-19): 127-134

Lehnen, D.; Barral, S.; Cardoso, T.; Grealish, S.; Heuer, A.; Smiyakin, A.; Kirkeby, A.; Kollet, J.; Cremer, H.; Parmar, M.; Bosio, A.; Knöbel, S., 2017: IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells. Human pluripotent stem cell (hPSC)-derived mesencephalic dopaminergic (mesDA) neurons can relieve motor deficits in animal models of Parkinson's disease (PD). Clinical translation of differentiation protocols requires standardization of produ...

Gerchik, F., 1959: Multiplication of phage. A short review on published data and the author's own observations concerning the morphology of phages, their chemical composition, the interaction with the sensitive bacterial cell and the stages of intracellular multiplication. The author a...

Juszczyk, J.; Rokossowski, H.; Krajewska, M.; Piatek, A., 1991: Humoral response in health service personnel after administration of hepatitis B vaccine Gen-H-B-Vax. Within the group of 260 members of medical staff, the presence of the HBV markers was found in 87 persons (33.5%). Vaccination, which was of a voluntary character, was initiated in the group of 75 persons according to the pattern of 0, 1, 6 months...

Fisher, Heriberto G., 1965: The flow and management of water sheds. Idia 215: 28-31

Krehbiel, J.D.; Langham, R.F., 1975: Eyelid neoplasms of dogs. A survey of 202 canine eyelid neoplasms was conducted to identify the prevalence of tumour types and their biological behaviour. Sebaceous gland tumours, melanomas, and papillomas made up 82.1% of the neoplasms studied. Sebaceous tumours were most...

Dedeoğlu, A.; Fisher, L.A., 1996: CNS actions of serotonin on cardiovascular function: nonadrenergic, noncholinergic mechanisms. The present studies investigated the mechanisms mediating the cardiovascular changes induced by intracerebroventricular injection of serotonin (5-HT; 100 nmol) in conscious rats. At 5 min after 5-HT injection, arterial pressure and plasma levels o...

Sarvella, Patricia, 1961: Morphological differences between cytoplasmic male-sterile and normal strains of maize. Asb Bull: 34

Weisz, J.R.; Suwanlert, S.; Chaiyasit, W.; Weiss, B.; Walter, B.R.; Anderson, W.W., 1988: Thai and American perspectives on over- and undercontrolled child behavior problems: exploring the threshold model among parents, teachers, and psychologists. Journal of Consulting and Clinical Psychology 56(4): 601-609

Sammataro, D., 1996: Mechanisms of bee resistance. American bee journal 136(8): 567-568