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An integration method for enzyme multiplied immunoassays

, : An integration method for enzyme multiplied immunoassays. Analytical Letters 18(11): 1321-1330

Integration methods for measuring substrates via homogeneous immunoassays are presented along with their theoretical bases. Integrals of differences in measured responses over time are used with enzyme multiplied immunoassay techniques and show unique relationships between the net integral data and analyte concentrations. Changes in indicator response signals are integrated over several minutes for drugs of forensic interest, and results for integrations of both published response curve data and laboratory assays are evaluated.


DOI: 10.1080/00032718508066213

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