+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Antiparkinsonian activity and behavioral effects of newer quinazolinones

, : Antiparkinsonian activity and behavioral effects of newer quinazolinones. Pharmacological Research Communications 19(9): 617-628

Sixteen new compounds 2-methylamino substituted phenyl-3-substituted anilino 4 (3H) quinazolinones (3-18) were prepared. All the compounds were evaluated for their antiparkinsonian activity and compared with bromocriptine. Compounds 10,15 and 18 showed better activity. These compounds also bind with the dopamine receptors in striatal membrane preparations of rat brain.


PMID: 3432327

Other references

Stern, H.; Carter, D.; Dikengil, A., 1986: Pulmonary nodule in an asymptomatic 64-year-old woman. The unexpected finding of a pulmonary nodule in an asymptomatic patient is a common clinical event. This paper examines the case of a 64-year-old woman who was discovered to have a small pulmonary nodule on routine examination. Differential diagno...

Khalid, A.; Mumtaz, K.; Ghufran, A.; Alishah, H.; Hamid, S.; Jafri, W., 2011: 45 25 gram versus 50 gram of 25% albumin in preventing renal impairment after large volume paracentesis in cirrhosis. Journal of Clinical and Experimental Hepatology 1(2): 153-153

Seiler, R., 1978: On the functional anatomy and physiological aspects of the auricle in Primates. Unknown

Maniwa, T.; Isaka, M.; Nakagawa, K.; Ohde, Y.; Okumura, T.; Endo, M.; Kondo, H., 2013: Chest-tube drainage is a sign of acute exacerbation of interstitial lung disease associated with lung cancer. Interstitial lung disease (ILD) is associated with primary lung cancer and an increased risk of postoperative acute exacerbation (AE). Although the preoperative factors associated with AE of ILD are well described, there is little information abou...

Hahn, R.G.; Nilsson, A., 1997: Cardiac output and ethanol monitoring of fluid absorption. The purpose of this experimental study was to find out whether central haemodynamic activity influences the precision of the ethanol method used to monitor fluid absorption during endoscopic surgery. Today, the nomograms used together with this mo...

Floate, K.D.; Fox, A.S., 2000: Flies under stress: A test of fluctuating asymmetry as a biomonitor of environmental quality. Fluctuating asymmetry (FA) has been proposed as a measure of environmental quality. The premise is that increased levels of environmental stress (e.g., chemical pollutants) are reflected by increased levels of FA within populations of organisms de...

Ulmet; Bachère; Askenazy; Ousset, 1988: Negative magnetoresistance in some dimethyltrimethylene-tetraselenafulvalenium salts: A signature of weak-localization effects. Physical Review. B, Condensed Matter 38(11): 7782-7788

Kandel, B.P.; Bhatta, D.R.; Shakya, G.; Upadhayay, B.P.; Dumre, S.P.; Poudyal, S.; Adhikari, N.; Acharya, D., 2016: In vitro Temocillin efficacy against extended spectrum β-lactamase producing multidrug resistant gram negative bacterial isolates from Nepal. Temocillin is relatively more stable against most β-lactamases and requires re-evaluation to include it in common clinical practice as a therapeutic alternative. At the National Reference Laboratory of Nepal, we evaluated multidrug resistance (MD...

O'Leary, H.M.; Mayor, J.Manuel.; Chi-Sang Poon; Kaufmann, W.E.; Sahin, M., 2017: Classification of respiratory disturbances in Rett Syndrome patients using Restricted Boltzmann Machine. Rett syndrome (RTT) is a severe neurodevelopmental disorder that can cause pervasive wakeful respiratory disturbances that include tachypnea, breath-holding, and central apnea. Quantitative analysis of these respiratory disturbances in RTT is cons...

Chan, M-Yen.; Heng, C-Kiat., 2007: Sequential effects of a high-fiber diet with psyllium husks on the expression levels of hepatic genes and plasma lipids. Expectation Maximization iterative reconstruction algorithms are being widely used in PET and SPECT imaging. The system probability matrix is usually calculated by using Monte Carlo simulations, since the analytical calculation is a rather complic...