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Barrett's ulcer report of two cases


, : Barrett's ulcer report of two cases. Gastroenterological Endoscopy 28(2): 327-332

We have presented two cases of Barrett's ulcer. Case 1 was a 69 years old man who was admitted because of palpitation. Radiological and endoscopical findings showed a huge ulcer in the lower esophagus. Case 2 was a 70 years old man who was admitted complaining oppression on the chest. Radiological findings showed a partial stricture of the lower esophagus and some barium spots on the proximal mucosa from the stricture. A map-like ulcer in the oral site from the stricture and a shallow ulcer in it were revealed by the esophagoscopy. Specialized columnar epithelia were found on the biopsied specimens from the background mucosa of both cases. These results suggested that the pathogenesis of our cases could be of acquired. Pirenzepine, sucralfate and cetraxate were administered for the treatment of each cases. Following this treatment, ulcers of both cases were cured without any complication. We would conclude that antacid and mucosal defensive agent were effective for the treatment of Barrett's ulcer.

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