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Bi directional deletions associated with insertion sequence is 4


, : Bi directional deletions associated with insertion sequence is 4. Molecular & General Genetics 185(2): 216-222

A new type of chromosomal rearrangement associated with a transposable element was described for insertion sequence IS4, in Escherichia coli. These rearrangements are deletions, in which the transposable element IS4 and DNA adjacent to it on either side is lost. The deletions are at least 10 times more frequent in the presence of IS4, than when the element is absent from that region. The formation of bidirectional deletions in > 1000 times more frequent than precise excision of IS4.

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