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Chromium 51 bleomycin in the diagnosis of tumors of the chest


, : Chromium 51 bleomycin in the diagnosis of tumors of the chest. Nuclear Medizin 24(2): 66-70

51Cr-bleomycin was used for the scintigraphic diagnosis of primary and secondary tumors of the thorax in 104 patients. The scintigraphy was performed using a .gamma. camera coupled to an on-line computer. Active lesions were scored using a semiquantitative scale of scores 0-5. Images were subdivided into 222 regions considered. In 72 of these, the presence of disease was diagnosed (64 malignant, 8 nonmalignant) and 150 regions were classified as free from disease. At the decision threshold of score 2, over-all sensitivity and specificity of the scintigraphic detection of malignant tumors amounted to 97 and 79%, respectively. Inflammatory changes displayed some detectable accumulation of 51Cr-bleomycin but scores attributed to these lesions did not exceed the values of 2.

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