+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Crystalline and molecular structure of the steroid acetoxy 17 beta cyano 5 alpha androstan 3 one/

, : Crystalline and molecular structure of the steroid acetoxy 17 beta cyano 5 alpha androstan 3 one/. Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry 34(1): 249-254

Crystalline 17.beta.-acetoxy-5.alpha.-cyanoandrostan-3-one, C22H31O3N, is orthorhombic, P212121, Z = 4, with a = 14.155 (7), b = 12.480 (6) and c = 10.940 (6) .ANG. The structure was solved by direct methods (MULTAN) and refined by the least squares method to a final R value of 5.4% with 1543 observed intensities measured on a diffractometer. The effect of the cyano group on the structure is discussed. The D ring has the expected half-chair conformation but the endocyclic torsional angles around C(15)-C(16) and C(16)-C(17) relate it more to that of a 17-one steroid rather than steroids with other .beta.-substituents (including hydroxy) on C(17).


Other references

Queiroga, R.-De-Cassia, R.E.; Madruga, M., S.; Galva, M.-De, S.; Da-Costa, R., G., 2005: Otimizacao das condicoes de extracao de compostos volaiteis em leite caprino utilizando a tecnica de extracao e concentracao simultanea. For identifying the compounds responsible for flavor requires procedures for performing the isolation and concentration of volatiles compounds from food raw macronutrient material with minimal effect on the original flavor. Several techniques have...

Magallanes, J., F.; Murruni, L.; Gomez, D.; Smichowski, P.; Gettar, R., 2008: An approach to air pollution source-receptor solution by angular distances. This study presents the analysis of two series of concentrations of airborne particulate matter (APM) collected in two exploratory campaigns aimed at elucidating the source-receptor problem (SRP) in the metropolitan area of Buenos Aires. Although...

Gordon,; Wright, A., 1998: DNA segregation: Putting chromosomes in their place. Recent studies provide evidence that bacterial chromosomes are replicated by an enzyme factory, the replisome, located at a fixed position at the center of the cell; the fixed replisome could be a major factor in determining chromosome order in th...

Kollef, M.H., 1993: Symptomatic pleural effusion after coronary artery revascularization: unsuspected pleural injury from internal mammary artery resection. A patient with a large left pleural effusion returned to her physician 4 weeks after CABG with saphenous vein grafts. After repeated investigations the cause of the effusion still could not be ascertained. Upon subsequent review it was noted that...

Paddenberg, R.; Huettemann, B.; Wolf, S.; Mannherz, H.G.orge, 1994: Endonuclease activities of the human pancreatic tumor cell line PaTu 8902LM during cycloheximide induced apoptosis. European Journal of Cell Biology 63(SUPPL 40): 30

Tribukait, B.; Forssberg, A.; Osterdahl, C., 1963: Leuococyte migration in partial body irradiation of guinea pigs. The concentration of segmented cells and lymphocytes in the blood 4 hours after partial body irradiation in guinea pigs differ markedly from that following a whole body dose. The significance of the high release of segmented cells into the blood t...

Crosswhite, P.; Sun, Z., 2013: Inhibition of phosphodiesterase-1 attenuates cold-induced pulmonary hypertension. Chronic exposure to cold caused pulmonary arterial hypertension (cold-induced pulmonary hypertension [CIPH]) and increased phosphodiesterase-1C (PDE-1C) expression in pulmonary arteries (PAs) in rats. The purpose of this study is to investigate a...

Mathisen, OA.; Macaulay, MC., 1983: The morphological features of a super swarm of krill, Euphausia superba. Memoirs of National Institute of Polar Research Special Issue, 153-164 No. 27

Birge, E.A.; Low, K.B., 1974: Detection of transcribable recombination products following conjugation in rec+, reCB- and recC-strains of Escherichia coli K12. Journal of Molecular Biology 83(4): 447-457

Khoroshavin I.V., 2002: Technological modeling of natural gas condensate stabilization process. Pages 350-351: