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Dependence between the rate of rna synthesis and the activity of ctp synthetase ec 6.3.4.2 in different tissues of rats and chickens


, : Dependence between the rate of rna synthesis and the activity of ctp synthetase ec 6.3.4.2 in different tissues of rats and chickens. Ukrainskii Biokhimicheskii Zhurnal 53(6): 54-57

The rate of total RNA synthesis determined by the method of Bukher and Sheffield in different tissues of rats and chickens decreases as follows: kidneys > liver > duodenal mucosa. The activity of CTP-synthetase determined in vitro and in vivo by the method suggested correlates with the rate of total RNA synthesis in the kidneys and liver tissues of rats and chickens. It is shown that 34-35% of CTP synthetized de novo in the chicken tissues and 31-34% in the rat tissues are used for RNA synthesis. At the same time 75-90% of CTP incorporated into RNA is formed by salvage pathway.

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