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Derivatives of tritium labeled serotonin in organ cultures of hamster pineal gland


, : Derivatives of tritium labeled serotonin in organ cultures of hamster pineal gland. Life Sciences 34(18): 1775-1782

The viability of the hamster pineal gland in organ culture was determined, and the effect of norepinephrine (NE) on [3H] serotonin derivatives was tested. In this study, elevated levels of melatonin (7-fold, P < 0.05), 5-hydroxytrytophol (5-fold, P < 0.001), 5-methoxytryptophol (1.78-fold, P < 0.05) and depressed levels of 5-hydroxyIAA (3.8-fold, P < 0.02) and methoxyIAA (1.78-fold, P < 0.05) were detected in the glands following the addition of NE to the medium. In a separate experiment, melatonin concentration in the media was also periodically measured by radioimmunoassay to determine the viability of the organ culture over a 4-day period. The melatonin level on day 2 (2321 .+-. 106 pg/gland) was significantly higher (P < 0.01) than on day 3 (1542 .+-. 86 pg/gland) or day 4 (805 .+-. 39 pg/gland). The viability of the hamster pineal organ culture was verified and it was shown that the gland responds to NE in vitro.

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Qian, J.; Zhu, X.; Tao, Y.; Zhou, Y.; He, X.; Li, D., 2015: Promotion of Ni2+ removal by masking toxicity to sulfate-reducing bacteria: addition of citrate. The sulfate-reducing bioprocess is a promising technology for the treatment of heavy metal-containing wastewater. This work was conducted to investigate the possibility of promoting heavy metal removal by the addition of citrate to mask Ni2+ toxic...

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Flamand, V.; Bouye, S.; Fantoni, J.; Ouzzane, A.; Villers, A., 2015: Not Available. Progres en Urologie 24(13): 896-896

Riester, A.; Spyroglou, A.; Neufeld-Cohen, A.; Chen, A.; Beuschlein, F., 2012: Urocortin-dependent effects on adrenal morphology, growth, and expression of steroidogenic enzymes in vivo. Urocortin (UCN) 1, 2, and 3 are members of the corticotropin-releasing factor (CRF) family that display varying affinities to the CRF receptor 1 (CRFR1 (CRHR1)) and 2 (CRFR2 (CRHR2)). UCNs represent important modulators of stress responses and are...

Branconnier R.J.; Branconnier M.E.; Walshe T.M.; Mccarthy C.; Morse P A., 1992: Blocking the calcium activated cytotoxic mechanisms of cholinergic neuronal death a novel treatment strategy for alzheimers disease. Psychopharmacology Bulletin 28(2): 175-181

Beloev I.T.mov, I.; TŭrnovskaR, 1985: Antiaggregants of thrombocytes in ischemic heart disease. Vutreshni Bolesti 24(5): 1-6

Delaunay, A., 1960: Pinocytosis and its discoverer. Vie Medicale 41: 1226-1230

Ejezie, F.; Nwagha, U., 2011: Zinc Concentration during Pregnancy and Lactation in Enugu, South-East Nigeria. There is no doubt that micronutrient deficiency is common in our environment. Replacements have thus been instituted without adequate information on specific and peculiar micronutrient needs of our people. Zinc is an essential micronutrient which...

Quintieri, C., 1955: The spread of erythromycin in intraocular fluids. Bollettino D'oculistica 34(4): 193-198

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