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Detection of human in vitro hapten specific antibody responses

, : Detection of human in vitro hapten specific antibody responses. Journal of Immunological Methods 65(1-2): 257-264

A microculture and radioimmunoassay is described which is capable of generating and detecting very small levels of human anti-DNP [dinitrophenyl] antibody. The antibody produced is hapten specific and the response is T-cell dependent. The microculture system described avoids the need for high serum supplements, mitogens, in vivo immunization or large cell numbers. As this system is simple, sensitive and reproducible it has considerable potential in the study of human immune response regulation and especially the role of lymphokines in human antibody responses.


PMID: 6197480

DOI: 10.1016/0022-1759(83)90322-8

Other references

McLean, A.A., 1978: Long range planning in occupational medicine. Journal of Occupational Medicine. 20(5): 359-359

Clark, R.A.; Ray, B.S., 1964: Bronson S. Ray: A Biographical Sketch. Clinical Neurosurgery 10: Xiii-Xxxi

Caillere Simonne; Henin Stephane, 1947: Sur une synthese de lantigorite a basse temperature. Describes a procedure for synthesizing antigorite at low temperatures. The success of the experiments indicates that serpentinization may be possible under surface conditions.

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Dalby, W., 1897: A Note as to when Incision of the Tympanic Membrane should be Performed in Acute Inflammation of the Middle Ear. British Medical Journal 2(1908): 213-214

Ragozzino, M.E.; Gold, P.E., 1991: Glucose effects on mecamylamine-induced memory deficits and decreases in locomotor activity in mice. Peripheral glucose administration attenuates the effects of muscarinic cholinergic antagonists on several measures, including spontaneous alternation, inhibitory avoidance, and locomotor activity. The present study examined glucose interactions wi...

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