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Effect of acetyl choline on atpase activity of brain synaptosomes in the ground squirrel citellus erythrogenus/


, : Effect of acetyl choline on atpase activity of brain synaptosomes in the ground squirrel citellus erythrogenus/. Zhurnal Evolyutsionnoi Biokhimii i Fiziologii 14(1): 88-90

In experiments in vitro at 37 and 17.degree. C, studies were made of the effect of ACh [acetylcholine] upon the activity of Mg- and Na, K-ATPase of brain synaptosomes of the ground squirrel in the summer and during winter hibernation. ACh (6 mM) decreases the activity of ATPases by 23-33% at 37.degree. C. During winter hibernation, the inhibitory effect of ACh is increased resulting in lower values of residual ATPase activity after the effect of ACh as compared with those obtained in summer period.

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