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Effect of naproxen on protein binding of warfarin in human serum


, : Effect of naproxen on protein binding of warfarin in human serum. Research Communications in Chemical Pathology and Pharmacology 15(2): 369-372

The effect of the non-steroidal anti-inflammatory agent naproxen on the protein binding of racemic warfarin in pooled human serum was determined by equilibrium dialysis. The free fraction of warfarin in serum increased practically linearly with increasing naproxen concentration. At the highest naproxen concentration tested (400 .mu.g/ml), the warfarin free fraction was 74% larger than the control free fraction value.

US$29.90

PMID: 981793


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Alderman, C.P.; Condon, J.T.; Gilbert, A.L., 2009: An open-label study of mirtazapine as treatment for combat-related PTSD. Posttraumatic stress disorder (PTSD) is common among war veterans. Antidepressants are effective in reducing symptoms and associated disability for some patients. To assess the effectiveness of mirtazapine for combat-related PTSD among veterans tr...

McGibony, J.T., 1965: The medical service of the Army of the United States of North America. Revista de la Sanidad Militar Argentina 64(3): 212-220

Weems, C.F.; Silverman, W.K., 2006: An integrative model of control: implications for understanding emotion regulation and dysregulation in childhood anxiety. Theorists and investigators have emphasized an important role for control in emotional problems such as anxiety and anxiety disorders in youth. However, the term "control" is subject to theoretical ambiguities because of the broad concep...

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Chiu, C.C.; Hamilton, R.M.; Gow, R.M.; Kirsh, J.A.; McCrindle, B.W., 2006: Evaluation of computerized interpretation of the pediatric electrocardiogram. The purpose of this research was to determine the frequency and factors affecting disagreement between pediatric cardiologist (MD1 or MD2) and the computer-assisted interpretation (CAI) of pediatric electrocardiograms from patients with heart dise...

Bojowald, M., 2001: Dynamical initial conditions in quantum cosmology. Loop quantum cosmology is shown to provide both the dynamical law and initial conditions for the wave function of a universe by one discrete evolution equation. Accompanied by the condition that semiclassical behavior is obtained at large volume,...

Bocchinfuso, G.; Bobone, S.; Mazzuca, C.; Palleschi, A.; Stella, L., 2011: Fluorescence spectroscopy and molecular dynamics simulations in studies on the mechanism of membrane destabilization by antimicrobial peptides. Since their initial discovery, 30 years ago, antimicrobial peptides (AMPs) have been intensely investigated as a possible solution to the increasing problem of drug-resistant bacteria. The interaction of antimicrobial peptides with the cellular m...

Sjaastad, O., 1984: Headache and the ameliorating effect of pregnancy: an editorial. Cephalalgia 4(4): 211-212

Helmer, O.M.; Fouts, P.J., 1937: Gastro-Intestinal Studies. Vii. The Excretion Of Xylose In Pernicious Anemia. Journal of Clinical Investigation 16(3): 343-349

Douglas C.Daly, 1980: Families of spermatophytes included in the flora of Peru published in Fieldiana. Brittonia 32(4): 548-550