+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effect of prostacyclin on platelet adhesion to rabbit arterial subendothelium

, : Effect of prostacyclin on platelet adhesion to rabbit arterial subendothelium. Prostaglandins 16(1): 17-22

The effect of prostacyclin on platelet aggregation and adhesion was investigated in everted pieces of rabbit abdominal aorta, from which the endothelium had previously been removed. Citrated human blood, to which different concentrations of prostacyclin (0.1-100 ng/ml) were added, was perfused through the vessels, after which sections were examined and evaluated by light microscopy. Prostacyclin inhibited thrombus formation at concentrations greater than 0.1 ng/ml, whereas 20 ng/ml were required to reduce the amount of adhesion to the subendothelial surface. Prostacyclin prevents thrombus formation at much lower concentrations than are needed to inhibit platelet-vessel wall interaction.


Other references

Daszykowski, M.; Walczak, B.; Massart, D.L., 2004: Density-based clustering for exploration of analytical data. Analytical and Bioanalytical Chemistry 380(3): 370-372

Heller, K.M., 1912: Ein neuer Dynastine aus Neu Guinea. 's Gravenhage Tijd schr: 307-310

Anonymous, 1982: Symposium on one-stage reconstructions. Clinics in Plastic Surgery 9(1): 1-127

Bonnet J.; Colle J.P.; Lorient Roudaut M.F.; Vergnes C.; Haissaguerre M.; Boisseau M.R.; Bricaud H., 1984: Efficacy and value of fibrinolytic drugs in proximal chronic venous thrombosis of the lower limbs. Forty patients (mean age = 56 .+-. 17 yr) hospitalized for proximal venous thrombosis of the lower limbs of over 7 days duration were treated with fibrinolytic drugs: streptokinase (SK) 28 cases, urokinase (UK) 12 cases. The efficacy of fibrinolyt...

Guo, X-Min.; Zhao, Y-Shan.; Chang, H-Xia.; Wang, C-Yong.; E.L.Ling.; Zhang, X-Ai.; Duan, C-Mi.; Dong, L-Zhi.; Jiang, H.; Li, J.; Song, Y.; Yang, X.Jerry., 2006: Creation of engineered cardiac tissue in vitro from mouse embryonic stem cells. Background - Embryonic stem (ES) cells can terminally differentiate into all types of somatic cells and are considered a promising source of seed cells for tissue engineering. However, despite recent progress in in vitro differentiation and in viv...

D'Alessandro, A.M.; Kalayoglu, M.; Pirsch, J.D.; Sollinger, H.W.; Reed, A.; Knechtle, S.J.; Hoffmann, R.M.; Belzer, F.O., 1991: Biliary tract complications after orthotopic liver transplantation. Transplantation Proceedings 23(3): 1956-1956

Tenbrink, T.; Andonova, E.; Schole, G.; Coventry, K.R., 2017: Communicative Success in Spatial Dialogue: The Impact of Functional Features and Dialogue Strategies. This paper addresses the impact of dialogue strategies and functional features of spatial arrangements on communicative success. To examine the sharing of cognition between two minds in order to achieve a joint goal, we collected a corpus of 24 ex...

Milowska, K.Z.; Ghorbani-Asl, M.; Burda, M.; Wolanicka, L.; Ćatić, N.; Bristowe, P.D.; Koziol, K.K.K., 2017: Breaking the electrical barrier between copper and carbon nanotubes. Improving the interface between copper and carbon nanotubes (CNTs) offers a straightforward strategy for the effective manufacturing and utilisation of Cu-CNT composite material that could be used in various industries including microelectronics,...

Krejcy, K.; Schwarzacher, S.; Raberger, G., 1993: Distribution and metabolism of N-G-nitro-L-arginine and N-G-nitro-L-arginine methylester in canine blood in vitro. The aim of the present study was to investigate the metabolism of the two NO-synthase inhibitors NG-nitro-L-arginine (L-NA) and NG-nitro-L-arginine methylester (L-NAME) in canine blood in vitro. Blood and plasma samples were incubated with L-NAME...

Lai, W.J.; Zeng, X.M.; Tan, B.A.; Wu, K.S.; Chan, C.Y.; Guan, W.X.; Faan, H.C., 1982: Identification of the causal organism of the bacterial wilt of mulberry. According to its properties and host range the pathogen was identified as race 1 of Pseudomonas solanacearum.