+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effect of seizures during pregnancy on seizure susceptibility in offspring

, : Effect of seizures during pregnancy on seizure susceptibility in offspring. Epilepsia 26(5): 421-423

The risk of epilepsy is higher in the offspring of epileptic mothers than epileptic fathers. it has been hypothesized that seizures during pregnancy may alter subsequent seizure susceptibility in the offspring. To test this hypothesis, pregnant rats were fully kindled during the first, second, or third trimesters. In addition, another group of pregnant rats were kindled during the first trimester and then stimulated daily to induce generalized tonic-clonic seizures until delivery. The rate of kindling in the offspring of the four groups was then compared with sham-operated controls. No significant difference in rate of kindling was noted between the offspring of sham-operated controls and kindled mothers. This study fails to support the hypothesis that maternal seizures during pregnancy lead to increased seizure susceptibility in the offspring.


PMID: 3840086

Other references

Minneva, N.; Litmanovich, K.; Vidayko, C.; Bodrova, N.; Zavarzina, O.; Priezjeva, L., 1998: The causes of post transfusional hemolitical immunological reactions. Vox Sanguinis 74(SUPPL 1): 1529, June

Birungi, H.; Mugisha, F.; Nsabagasani, X.; Okuonzi, S.; Jeppsson, A., 2001: The policy on public-private mix in the Ugandan health sector: catching up with reality. An informal public-private mix in the health sector has always existed in Uganda, and policymakers, planners and the public in general have taken this for granted. There is now renewed effort to develop a comprehensive policy on the mix, but the p...

Sharp, D., 2004: As we said... Lancet 364(9436): 744-744

Dick, U., 1963: Serum cholesterol values in clinically ealthy dogs estimated by the ultra-micromethod.. Cholesterol was estimated colorimetrically by the method of Caraway and Fanger (Amer. J. Clin. Pathol., 1955, 25, 317). Values for a standard sample were low by 2.7% and those for serum also were less than by the method of Schonheimer and Sperry m...

Heinberg, C.J., 1947: A new synthetic anti-histaminic substance, antistine. Eye, Ear, Nose & Throat Monthly 26(12): 639-641

Stein E., 1989: The classification of the Arzberg Series (Saxothuringian, northeastern Bavaria) derived from the perspective of structural geology. Zentralblatt fuer Geologie und Palaeontologie, Teil I: Allgemeine, Angewandte, Regionale und Historische Geologie 1989(1-2): 398

Kuo, R.L.; Paterson, R.F.; Bledsoe, S.B.; Coe, F.L.; Evan, A.P.; Lingeman, J.E., 2003: Endoscopic renal papillary biopsies A novel technique of tissue retrieval for histologic studies in nephrolithiasis patients. Journal of Urology 169(4 Supplement): 490, April

Goldstein B.D., 1985: Acrylamide neurotoxicity altered spinal monosynaptic responses to quipazine a serotonin agonist in cats. The effects of the serotonin agonist quipazine on the spinal monosynaptic reflex (MSR) were investigated in acrylamide-treated cats. Cats were administered 30 mg/kg acrylamide (ACR) for 10 days, and the MSR and spontaneous ventral root discharge (...

Burlatsky; Moreau, 1995: Apparent rate constant for diffusion-controlled three-molecule reactions. Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics 51(3): 2363-2367

Anonymous, 1975: Planning seating accommodation. Hospital Equipment & Supplies 21(3): 44-45