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Effects of anticonvulsants on the psychotropic activity of tranquilizers in their combined administration in an experiment


, : Effects of anticonvulsants on the psychotropic activity of tranquilizers in their combined administration in an experiment. Farmakologiya i Toksikologiya (Moscow) 50(4): 15-18

Effects of anticonvulsants (phenobarbital, hexamidine, benzonal, diphenine, chloracon, trimethin, carbamazepine) on the psychotropic activity of tranquillizers (diazepam, chlordiazepoxide, meprotan, trioxazine, mebicar) were studied in experiments on mice and rats. Thirteen combinations were studied by using corazol test, "open field" and elementary-defensive conditioned response technique. According to all three tests the psychotropic activity was enhanced to the greatest degree by administration of hexamidine in combination with chlordiazepoxide.

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