geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Erythroid progenitors erythropoietic burst forming units and erythroid colony forming units in acute leukemia


, : Erythroid progenitors erythropoietic burst forming units and erythroid colony forming units in acute leukemia. Journal of Clinical Pathology (London) 32(7): 666-669

Bone marrow erythroid progenitor cells were examined from 50 cases of acute leukemia and from 20 normal subjects using an in vitro semisolid culture method. Numbers of primitive erythroid progenitor cells (BFU-e) and later-stage erythroid progenitor cells (CFU-e) were remarkably depressed in patients with acute leukemia in active phase. BFU-e and CFU-e recovered to within normal range when the patients achieved remission. Peripheral blood BFU-e of children with acute lymphocytic leukemia in remission were also examined and found to have values not significantly different from control subjects. There was no distinct correlation between the numbers of erythroid bursts or colonies and the duration of remission in patients with acute leukemia in remission. The reduction of BFU-e and CFU-e in active acute leukemia suggests the involvement of erythropoietic progenitors in the pathophysiology of this type of leukemia.

US$29.90


Other references

Darnall, R.A.; Curran, A.K.; Filiano, J.J.; Li, A.; Nattie, E.E., 2001: The effects of a GABA(A) agonist in the rostral ventral medulla on sleep and breathing in newborn piglets. Study Objectives: Abnormalities in the rostral ventral medulla (RVM) in human infants may contribute to the etiology of the sudden infant death syndrome (SIDS) or a subset of SIDS, by interfering with cardiorespiratory and arousal responses to phy...

Schmitt, J.; Abbott, J.Haxby., 2016: Global ratings of change do not accurately reflect functional change over time in clinical practice. Retrospective longitudinal cohort study. To determine whether the global rating of change (GROC) is valid for assessing functional change over time in the clinical setting, and whether validity decreases as length of recall increases. The validity...

Pitson, D.; Bhaskaran, V.; Bond, H.; Yarnold, R.; Drewett, R., 1994: Effectiveness of knee replacement surgery in arthritis. This study examined the effectiveness of knee replacement surgery in an elderly population suffering from arthritis. Four questionnaires which measured pain, mobility, anxiety, depression and social isolation were completed by the study group befo...

Ackzell, L., 1994: Forest regeneration by nature and man - studies in boreal Sweden emphasizing genetic aspects. A dissertation containing a summary report (44 pp., including 8 pp. of ref.) and the full text of 5 papers (published or in press) written or co-written by L. Ackzell. The study is based on observations of natural and artificial regeneration of Pi...

Aoki, T.; Nishizono, M.; Niina, H.; Inatsu, H.; Komidori, H.; Itano, T.; Daimon, Y.; Haraguchi, Y.; Yoshida, T.; Tanaka, K., 1990: A case of spontaneous mesenteric hematoma and a review of 17 cases in Japan. A 47 year-old male was admitted to Miyazaki Medical college Hospital for further evaluation of an abdominal mass in the left upper quadrant. Abdominal ultrasound (US) and abdominal computed tomography (CT) showed two cystic masses in the mesenteri...

Abdalla, H.; Matambo, T.S.; Koekemoer, L.L.; Mnzava, A.P.; Hunt, R.H.; Coetzee, M., 2007: Insecticide susceptibility and vector status of natural populations of Anopheles arabiensis from Sudan. Species composition, blood meal source, sporozoite infection rate, insecticide resistance and the kdr mutations were investigated in the Anopheles gambiae complex from 13 sentinel sites in central Sudan. Species identification revealed that 89.5%...

Sarna, M.; Ware, R.S.; Lambert, S.B.; Sloots, T.P.; Nissen, M.D.; Grimwood, K., 2017: Timing of First Respiratory Virus Detections in Infants: A Community-Based Birth Cohort Study. Determining timing of first virus detection episodes (fVDEs) for different respiratory viruses in infants identifies risk periods and informs preventive interventions, including vaccination. We describe the ages and nature of fVDEs in an infant bi...

Salvati, F.; Rossi, F.; Limbucci, N.; Pistoia, M.L.; Barile, A.; Masciocchi, C., 2008: Mucoid metaplastic-degeneration of anterior cruciate ligament. Mucoid degeneration of the anterior cruciate ligament (ACL) is a pathological state not yet well morphologically defined, involving people without history of knee instability or significant trauma, and causing important pain. The aim of this study...

Rasmussen, S.; Talleruphuus, U.; Wandall, J.H., 1995: Pneumococcal tricuspid valve endocarditis. Endocarditis caused by pneumococci is a rare disease and cases that only affect the tricuspid valve represent less than 1% of all cases of endocarditis. A case presenting with a primary pneumonia and septicaemia is described. Due to persistent fev...

Mazeh, H.; Mizrahi, I.; Ilyayev, N.; Halle, D.; Brücher, B.; Bilchik, A.; Protic, M.; Daumer, M.; Stojadinovic, A.; Itzhak, A.; Nissan, A., 2013: The Diagnostic and Prognostic Role of microRNA in Colorectal Cancer - a Comprehensive review. The discovery of microRNA, a group of regulatory short RNA fragments, has added a new dimension to the diagnosis and management of neoplastic diseases. Differential expression of microRNA in a unique pattern in a wide range of tumor types enables...