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Factors affecting cardio vascular responses to stimulation of hypothalamus in the rat


, : Factors affecting cardio vascular responses to stimulation of hypothalamus in the rat. Experimental Neurology 51(1): 188-206

Changes in heart rate and arterial pressure to electrical stimulation of 161 histologically verified sites in the hypothalamus and preoptic area were investigated in 60 artificially respired rats under chloralose anesthesia. Stimulation at 80 Hz of most nuclei of the posterior hypothalamus elicited hypertension and bradycardia; stimulation of sites in these nuclei in vagotomized rats elicited hypertension and tachycardia. Stimulation of the dorsomedial and premamillary nuclei often elicited hypotension and bradycardia; stimulation of these nuclei in vagotomized rats elicited hypertension and tachycardia. Hypertension elicited from the lateral and anterior hypothalamus by 80-Hz stimulation was eliminated or was changed to hypotension during stimulation at 8 Hz. Hypotension and bradycardia elicited from the ventral preoptic area were changed to hypertension and tachycardia after vagotomy; bradycardia, but not hypotension, elicited from the dorsal preoptic area was abolished by vagotomy or methyl atropine administration. Responses elicited from 54 sites in 31 urethane-anesthetized rats were similar to those elicited from vagotomized chloralose-anesthetized rats. Accurate localization of stimulation sites, stimulation parameters and anesthetic agents are important in studies of central neural control of the cardiovascular system.

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PMID: 1261634


Other references

Herriott M.; Leu R., 1991: Macrophage antibody dependent cellular cytotoxicity is mediated by an oxidative mechanism which is independent to tumor necrosis factor and nitric oxide production. Journal of Leukocyte Biology (SUPPL 2): 54-55

Bokma, J.; Timmer, J., 1983: What does the family think? Results of a survey among visitors to the medical care department of a nursing home. In order to obtain a fuller understanding of the various ideas behind the evaluation of care as provided by nursing homes, 42 regular and frequent visitors of a nursing home, participated in 'open-attitude' interviews. These people had t...

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Radzikowski, T.; Zalewski, T.K.; Kapuscinska, A.; Chorzelski, T.P.; Sulej, J.; Beutner, E.H.; Kumar, V.; Rossi, T., 1988: Short stature due to unrecognized celiac disease. European Journal of Pediatrics 147(3): 334-335

Brandwine, S.; Shachak, M., 1996: The effect of soil moisture patchiness on dispersal and abundance of invertebrates in the Negev desert. Bulletin of the Ecological Society of America 77(3 SUPPL PART 2): 51

Kamyszek, Franciszek, 1965: The house-fly as carrier of fungal infections. Seven hundred ninety-five flies on artificial media infected with the fungus Trichophyton acuminatum (Sabouraud) were investigated. Results show that the flies can carry pathogenic fungi passively into artificial media. The number of carrier flies...

Wegener, G.; Krause, U.; Thuy, M., 1990: Fructose 2,6-bisphosphate and glycolytic flux in skeletal muscle of swimming frog. Glycolytic flux in skeletal muscle is controlled by 6-phosphofructokinase but how this is achieved is controversial. Brief exercise (swimming) in frogs caused a dramatic increase in the phosphofructokinase activator, fructose 2,6-bisphosphate, in...

Frampton, G.; Perry, G.J.; Chan, T.M.; Cameron, J.S., 1992: Significance of anticardiolipin and antiendothelial cell antibodies in the nephritis of lupus. Contributions to Nephrology 99: 7-16

Szefler, S.J., 2012: Advances in pediatric asthma in 2011: moving forward. Last year's "Advances in pediatric asthma" concluded with the following statement: "Perhaps new directions in personalized medicine and improved health care access and communication will help maintain steady progress in allevia...

Carlson, Rf, 1975: Status and performance of M.26 rootstock. Summer 56 (3) 14