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Gangliosides of regenerating rat liver

, : Gangliosides of regenerating rat liver. Doklady Akademii Nauk SSSR Seriya Biologiya 223(6): 1481-1483

The changes in the content of gangliosides in regenerating rat liver and in hepatoma 27 of rats in comparison with the normal liver were studied. The deviations from the norm observed in the regenerating liver and in hepatoma were directly opposite with respect to a number of parameters. In hepatoma the content of lipid-bound sialic acids increased in comparison with the norm and decreased considerably in rapidly proliferating tissue of the regenerating liver. The characteristics of the ganglioside composition of hepatomas are due not to rapid growth as such but are related with the malignant process.


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