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Granulocytic sarcoma of the cervix as a primary manifestation case without overt leukemic features for 26 months

, : Granulocytic sarcoma of the cervix as a primary manifestation case without overt leukemic features for 26 months. Cancer 40(6): 3030-3037

A case of granulocytic sarcoma involving the uterine cervix as primary manifestation without evidence of leukemia is presented. It was followed by neurological symptoms 19 mo. later and a right breast mass 26 mo. after the initial cervical lesion, but still with no evidence of leukemia. Two years and four months after onset, soft tissue and skin nodules developed and rare blastic cells appeared on peripheral blood smear. The patient terminally developed acute granulocytic leukemia with a rapidly downhill course. The differential diagnosis of granulocytic sarcoma and histiocytic lymphoma is discussed. The literature is reviewed with emphasis on the clinical and pathological probles that arise when the tumor presents in an unusual location without peripheral blood manifestation of leukemia.


PMID: 338140

DOI: 10.1002/1097-0142(197712)40:6<3030::aid-cncr2820400640>;2-#

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