geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Hemorrhage and hemosiderin


, : Hemorrhage and hemosiderin. Journal of Submicroscopic Cytology 11(2): 271-291

Whenever, wherever and however hemorrhage occurs, certain basic mechanisms (with minor site dependent variations) are deployed by the organism to dispose off extravasated erythrocytes. The key mechanism here is the phagocytosis of erythrocytes (erythrophagocytosis and of products of lysis (erythrocyte ghosts and Hb) by macrophages and other cells leading to the formation of heterophageosomes and heterolysosomes where digestion of injested material ensures. This leads to the formation of 3 types of lysosomal bodies: myelinosomes containing whorled osmiophilic membranes, siderosomes containing electron-dense Fe-containing particles (i.e., hemosiderin) and myelinosiderosomes containing myelinoid membranes and hemosiderin. There has been much controversy about the nature and chemical composition of hemosiderin found after hemorrhage. Ultrastructural studies show that this is a pigment derived by digestion of Hb in the lysosome (siderosome) while electron probe X-ray analytical studies indicate that hemosiderin is essentially a condensate of hydrated ferric oxide and that any other element (e.g., P or S) present probably reflects the presence of undigested organic material in the siderosome.

US$29.90


Other references

Durán Barquero, C.; Serrano Vicente, J.; García Bernardo, L.; Domínguez Grande, M.L.; Rayo Madrid, J.I.; Infante de la Torre, J.R.; Sánchez Sánchez, R., 2010: Inguinal herniation of a bladder diverticulum, diagnosed by PET-CT. Revista Espanola de Medicina Nuclear 29(1): 36-37

Michel, A.C., 2011: Prescribers, is the relationship with your "authorized agent" explicit, transparent and proper?. Tennessee Medicine 104(8): 35-36

Nausch, N.; Mutapi, F., 2017: Group 2 ILCs: A way of enhancing immune protection against human helminths?. Group 2 innate lymphoid cells (ILC2s) play crucial roles in type 2 immune responses associated with allergic and autoimmune diseases, viral and helminth infections and tissue homoeostasis. Experimental models show that in helminth infections ILC2s...

Ong, A.C.; Fine, L.G., 1994: Tubular-derived cytokines and human renal disease progression. Nephrology, Dialysis, Transplantation 9(5): 471-472

Wallace, Z.S.; Stone, J.H., 2015: An update on IgG4-related disease. IgG4-related disease (IgG4-RD) is a recently described fibroinflammatory condition that can affect nearly any organ. Our knowledge of this condition--its manifestations, diagnosis, pathogenesis and treatment--is expanding rapidly. This review high...

Schuschnig, C.; Waltl, B.; Erlacher, W.; Reddy, B.; Stoik, W.; Kapral, S., 1999: Intubating laryngeal mask and rapid sequence induction in patients with cervical spine injury. The Intubating Laryngeal Mask (FastrachTM), a modified conventional laryngeal mask airway, and its prototype cuffed silicone tube, continue to be an appropriate intubating tool in combination with fibreoptic bronchoscopy in the emergency situation...

Shepherd, E.J.W.; Woodgate, R.L., 2010: Cancer survivorship in children and young adults: a concept analysis. Survivorship has been described in a variety of ways. Understanding how survivorship is applied in the context of childhood cancer survivors is important to the practice of pediatric nursing because it will offer nurses new possibilities for provi...

Connell, K.; Borg, M.B.; Cavaliero, L.; Ross, I.; Watchmaker, A., 1992: From coma to discharge. The story of a roller coaster recovery. Nursing 22(6): 44-50

Barrett S.C.H.; Shore J.S., 1985: Dimorphic incompatibility in turnera hermannioides turneraceae. Tunera hermannioides (Turneraceae) is a distylous, diploid, perennia restricted to open, sandy sites in northeastern Brazil. Four populations sampled in Sergipe contained equal proportions of long- and short-styled plants. The style and stamen dim...

Jackson, G.L., 1975: Calculated low dose radio-iodine therapy of thyrotoxicosis. International Journal of Nuclear Medicine and Biology 2(2): 80-81