+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Histopathological characteristics of stromal cells in trophoblastic disease

, : Histopathological characteristics of stromal cells in trophoblastic disease. Nihon Sanka Fujinka Gakkai Zasshi 40(1): 31-35

The histopathological characteristics of stromal cells in trophoblastic diseases remain unknown, though determination of malignancy depends on the existence of stromal elements in villi. Thus, we tried to clarify the characteristics and role of stromal cells in the development of diseases. The mitosis index (MI) of stromal cells and cytotrophoblasts, and the frequency of vessels observed in the stroma were examined. The results were as follows: 1) Complete moles were characterized by high MI values for stromal cells and cytotrophoblasts. They were similar to the ones from normal villi. 2) In partial moles, the MI values for both cells were remarkably low. 3) Invasive moles showed low stromal MI and high cytotrophoblastic MI values. 4) The frequency of blood vessels observed in the stroma was low in complete and invasive moles, though it was high in partial moles. the present results which showed histopathological differences in stromal elements in partial and complete moles, may correspond to the difference in their pathogenesis. And it is possible to assume that the decrease in stromal MI values in invasive mole play an important role in the abnormal proliferation of trophoblasts.


PMID: 2832490

Other references

He, G.; Yang, B.Z.; Roe, D.S.; Teramoto, R.; Aleck, K.; Grebe, T.A.; Roe, C.R.; Ding, J.H., 1999: Identification of two novel mutations in the hypoglycemic phenotype of very long chain acyl-CoA dehydrogenase deficiency. Very long chain acyl-CoA dehydrogenase (VLCAD) catalyzes the initial step of long chain fatty acid oxidation in the mitochondria. Patients with VLCAD deficiency have recently been observed with two clinical phenotypes. The cardiac form presents wi...

Chave, J.; Coomes, D.; Jansen, S.; Lewis, S.L.; Swenson, N.G.; Zanne, A.E., 2009: Towards a worldwide wood economics spectrum. Wood performs several essential functions in plants, including mechanically supporting aboveground tissue, storing water and other resources, and transporting sap. Woody tissues are likely to face physiological, structural and defensive trade-offs...

Loncaric, C.; Manabe, K.; Kobayashi, S., 2003: Alkaline salt-catalyzed aza Diels-Alder reactions of Danishefsky's diene with imines in water under neutral conditions. Two- or three-component aza Diels-Alder reactions of Danishefsky's diene with imines or aldehydes and amines in water took place smoothly under neutral conditions in the presence of a catalytic amount of an alkaline salt such as sodium trifla...

Kusano E.; Baba K.; Doi Y.; Hashiba K., 1990: A study for the proliferation and the calcium fluxes of cultured vascular smooth muscle cells vsmc from dahls rats. Japanese Circulation Journal 54(7): 764-765

Horowitz, A.M.; Suomi, J.D.; Peterson, J.K.; Lyman, B.A., 1977: Effects of supervised daily dental plaque removal by children: II. 24 months' results. After two school years of a supervised daily plaque-removal program in school, children in the treatment group showed a significant reduction in plaque and gingival inflammation scores compared with children in the control group. However, differen...

Vandenbussche, F.; D.L.euw, I.; Vandemeulebroucke, E.; D.C.ercq, K., 2010: Emergence of bluetongue serotypes in Europe, part 1: description and validation of four real-time RT-PCR assays for the serotyping of bluetongue viruses BTV-1, BTV-6, BTV-8 and BTV-11. The control of bluetongue virus (BTV) in Central-Western Europe is greatly complicated by the coexistence of several BTV serotypes. Rapid, sensitive and specific assays are therefore needed to correctly identify the currently circulating BTV serot...

Athwal, B.S.; Gale, A.N.; Brett, M.M.; Youl, B.D., 2001: Wound botulism in the UK. Lancet 357(9251): 234-234

Shi, H.; Zhao, N.; Ding, D.; Liang, J.; Tang, B.Zhong.; Liu, B., 2014: Fluorescent light-up probe with aggregation-induced emission characteristics for in vivo imaging of cell apoptosis. In this paper, a new live-cell permeable, fluorescent light-up probe comprised of a hydrophilic caspase-specific Asp-Glu-Val-Asp (DEVD) peptide and a hydrophobic tetraphenylethene pyridinium unit has been developed for in vivo cell apoptosis imagi...

Cheney C.M.; Lash J.W., 1980: Correlation between fibronectin and an increase in cell adhesion in chick somites. European Journal of Cell Biology 22(1): 422

Shlezinger N.A.; Zorkin F.P.; Larina A.P., 1940: Khimicheskiy sostav Ozinskikh soley i perspektivy ikh promyshlennogo ispolzovaniya. Chemical composition of Permian salt deposits of the Ozin salt dome, Volga river region, Russia.