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Iatrogenic hyper osmolality in a neo nate

, : Iatrogenic hyper osmolality in a neo nate. South African Medical Journal 60(26): 996-998

An infant presented in the 1st wk postpartum with markedly elevated serum osmolality of unknown origin. The cryptic osmols were identified as glycerol and alcohol and were traced to the contents of a local phenobarbitone elixir administered to control neonatal convulsions. This highlights the importance of recognizing the potential dangers inherent in the nominally inert components of medication and stresses the extreme care required when modifying well-established formulations.


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