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Identification and fibrinolytic activity of the microorganism incitants of common urinary infections


, : Identification and fibrinolytic activity of the microorganism incitants of common urinary infections. Mikrobiologicheskii Zhurnal (Kiev) 45(5): 83-87

Bacteriological examination of 241 patients in a urological clinic showed that the uroinfectious process (pyelonephritis) induced by common microbes promoted development of nephrolithiasis in 35-45% of the cases. From 119 nephrolithiasis patients (47%), Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa, Staphylococcus, Streptococcus, Klebsiella, etc., were isolated. Of the isolates, 34% possessed fibrinolytic properties. Thus, the common agents of uroinfection are highly virulent in the urinary system due to their proteolytic and fibrinolytic properties. These results provide evidence for a definite etiological and pathogenetic role of uroinfection in nephrolithiasis development.

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