+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immune mechanism of rats to nippostrongylus brasiliensis in vitro part 1 the influence of humoral and secretory antibodies and mast cells

, : Immune mechanism of rats to nippostrongylus brasiliensis in vitro part 1 the influence of humoral and secretory antibodies and mast cells. Zeitschrift fuer Parasitenkunde 50(1): 57-66

The influence of humoral and secretory antibodies as well as various cell supplements on N. brasiliensis was tested in vitro. Adult Spraque-Dawley rats approximately 12 wk of age were used. Various tests were conducted with the addition of serum or secretory antibodies of repeatedly infected and immune rats to the medium. In these tests, there was no difference in growth or mortality rate exhibited between larval or adult N. brasiliensis. This is in contrast to cultures where serum and secretory antibodies of non-infected animals were used. A 100% degranulation of mast cells from infected rats occurred within 14-22 h in cultures of adult N. brasiliensis. Variations were not noticed in viability of N. brasiliensis kept in media for 10 days with or without cell supplements, or with or without sera of infected or non-infected rats. There was no variation in the development of, or a higher mortality rate in the larval stages and adult Nippostrongylus in media containing sera and secretory antibodies of infected or non-infected rats.


Other references

Hallstrom, C.K.; Gardner, A.M.; Gardner, P.R., 2003: Nitric oxide metabolism in mammalian cells Substrate and inhibitor profiles of a microsomal no dioxygenase. Free Radical Biology & Medicine 35(Supplement 1): S98

Themelis, D.G.; Tzanavaras, P.D., 2002: Solvent extraction flow-injection manifold for the simultaneous spectrophotometric determination of free cyanide and thiocyanate ions based upon on-line masking of cyanides by formaldehyde. This study reports a sensitive solvent extraction flow-injection (FI) method for the simultaneous spectrophotometric determination of free cyanide and the thiocyanate in human saliva and pralidoxime solutions. Cyanide and thiocyanate form colored...

Stamatovic, S.; Jovanovic, M., 1972: Study of colloid-osmotic pressure (COP) of blood serum proteins in cattle and swine by indirect method after Keys. II. Colloid-osmotic pressure in swine. Veterinarski glasnik: 6 (11) 807-813

Siedle, B.; García-Piñeres, A.J.; Murillo, R.; Schulte-Mönting, Jürgen.; Castro, V.; Rüngeler, P.; Klaas, C.A.; D.C.sta, F.B.; Kisiel, W.; Merfort, I., 2004: Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kappaB. Sesquiterpene lactones (SLs) are the active compounds of a variety of traditionally used medicinal plants from the Asteraceae family. They are known to possess a considerable antiinflammatory activity in different inflammation models. They inhibit...

Kuznetsov V.G., 1991: Chert formations in Oxfordian carbonate deposits of North Ossetia. Byulleten' Moskovskogo Obshchestva Ispytateley Prirody, Otdel Geologicheskiy: , Pages 110-116. 1991.

Shin, K.; Udachin, K.A.; Moudrakovski, I.L.; Leek, D.M.; Alavi, S.; Ratcliffe, C.I.; Ripmeester, J.A., 2013: Methanol incorporation in clathrate hydrates and the implications for oil and gas pipeline flow assurance and icy planetary bodies. One of the best-known uses of methanol is as antifreeze. Methanol is used in large quantities in industrial applications to prevent methane clathrate hydrate blockages from forming in oil and gas pipelines. Methanol is also assigned a major role a...

Nkosi, S.A.; Kirsten, J.F.; Bhembe, S.M.; Bach, H.J.S. von, 1994: The role of traditional institutions in rural development: the case Bogosi (chieftainship). Tribal authorities or the chieftainship in traditional African societies are regarded as indigenous organizations. Rapid emergence of new social movements, better understanding of the logic of cooperation, ability of a variety of organizational fo...

Pyszko, J.; Strosznajder, J.B., 2015: Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells. Sphingosine kinases (Sphk1/2) are crucial enzymes in regulation of the biostat between sphingosine-1-phosphate (S1P) and ceramide and play an important role in the pathogenesis/pathomechanism of Alzheimer's disease (AD). These enzymes synthes...

Saito, M.; Yamazaki, M.; Maeda, T.; Matsumura, H.; Setoguchi, Y.; Tsuboi, R., 2012: Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction. Keloid is a clinically intractable disease that causes disfigurement, itching, and pain due to abnormal proliferation of fibroblasts and production of collagen. Pirfenidone is a novel anti-fibrotic agent that inhibits the progression of fibrosis o...

Andreae, B., 1977: Farm location problems related to agricultural production. Some historical preliminary remarks to the meeting theme. Schriften 4 3-6