geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Increased peritoneal permeability in patients with peritonitis undergoing continuous ambulatory peritoneal dialysis


, : Increased peritoneal permeability in patients with peritonitis undergoing continuous ambulatory peritoneal dialysis. European Journal of Clinical Pharmacology 28(2): 187-192

The distribution of cefuroxime (250 mg) was studied in patients with renal failure undergoing continuous ambulatory peritoneal dialysis (CAPD). Uninfected patients (10) received the drug i.v. and i.p. while 9 patients with peritonitis were randomly allocated to i.v. or i.p. administration. Samples were taken over the first 6 h dialysis period. In the infected patients, more drug (P < 0.01) crossed into the peritoneal cavity following i.v. injection and reached the systemic circulation following i.p. administration than in the uninfected group. This increased permeability of the peritoneal membrance during infection may result in unexpected systemic toxicity in patients treated with i.p. antibiotics.

US$19.90

PMID: 3987798

DOI: 10.1007/bf00609690


Other references

Wei, Z.; Fu, Y.; Zhou, E.; Tian, Y.; Yao, M.; Li, Y.; Yang, Z.; Cao, Y., 2015: Effects of niacin on Staphylococcus aureus internalization into bovine mammary epithelial cells by modulating NF-κB activation. Niacin is a precursor of coenzymes NAD and NADP and plays a critical role in electron transfer during the metabolic process. In addition to its nutrimental function, niacin has long been used for the treatment of lipid disorders and cardiovascular...

Floch, H.; Fauran, P., 1956: Two species of the genus Trombicula (Acariens, Trombiculidae) new for the fauna of French Guiana: Trombicula alfreddugesi (Oudemans, 1910) and Trombicula sinnamaryi n. sp. Publication. Cayenne, French Guiana. Institut Pasteur de la Guyane Francaise et de L'inini 17(405): 1-7

Sen P.K., 1968: Human heart homo transplantation donor recipient criteria surgical technique. American Journal of Cardiology 22(6): 826-832

Mäkelä, J.; Kairaluoma, M.I., 1986: Reoperation for colorectal cancer. In a retrospective study, the results of reoperation for colorectal cancer were evaluated in 43 consecutive cases. The overall postoperative mortality was 9% and the morbidity 47%. The mean survival time was 20 +/- 23 months, median 14 months. The...

Gina, A.R.; Polanowicz, U.; Pieczyrak, R.; Kucharz, E.J., 1995: Receptor CD23 and sCD23--structure and biological function. Polskie Archiwum Medycyny Wewnetrznej 94(5): 436-441

Carikov, N.N., 1964: Effect of feathermeal and meal of viscera from table poultry on the secretory and motor functions of the digestive tract of laying hens. Six Russian White hens had duodenal fistulae and 3 had electrodes implanted in the walls of gizzard and duodenum. At 20 h after feeding the flow of chyme from the duodenal fistula was 4 to 6 ml per h. Test feeds affected the chyme in 3 to 5 min. F...

Ingram T.T.S., 1969: Developmental disorders of speech. Vinken, P 4 And G W Bruyn (Edited By) Handbook Of Clinical Neurology Vol I Disturbance Of Nervous Function Ix + 701p Illus John Wiley And Sons, Inc : New York, N Y U S A And Sons, Inc : New York, N Y U S A 407-442

Corvalan J.; Straffon R.A.; Kiser W.S.; Hewitt C.B.; Stewart B.H., 1969: Clinical experience with 157 human renal homo transplantations. Urologia Panamericana 1(1): 32-38

McCarthy, W.H., 1972: Egotistical specialists' and nursing students. Nursing Times 68(3): 84-85

Whelpdale, D.M., 1983: Acid deposition: distribution and impact. The concept of acid deposition is explained and its geographical distribution described. More detailed measurements available from North America and western Europe are discussed. The damage caused by acid deposition to man-made structures, health,...