geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Inhaled benzene feto toxicity in rats


, : Inhaled benzene feto toxicity in rats. Toxicology and Applied Pharmacology 46(1): 9-18

Groups of pregnant Sprague-Dawley rats were exposed to 100, 300 and 2200 ppm of benzene vapor in air for 6 h daily on days 6-15 of gestation. The mean maternal body weight gain of the 2200 ppm group was significantly depressed. However, the incidence of resorption was not affected. The mean fetal body weight and crown-rump length were significantly lower than the corresponding control groups only at the highest exposure level. Soft tissue examination revealed no significant increase in the incidence of anomalies among the exposed animals. Skeletal examinations showed a significant increase in the number of fetuses with delayed ossification of sternebrae in the 300 and 2200 ppm groups. The female offspring appeared to be affected to a greater extent than male fetuses with respect to the incidence of delayed ossification of sternebrae. The litter incidence of missing sternebrae was significantly increased in the 100 and 2200 ppm exposure groups. The incidence of missing sternebrae was significantly increased in female but not in male offspring at 2200 ppm of benzene.

US$29.90

PMID: 725954


Other references

Connolly, A.T.; Jensen, A.L.; Baker, K.B.; Vitek, J.L.; Johnson, M.D., 2016: Classification of pallidal oscillations with increasing parkinsonian severity. The firing patterns of neurons in the basal ganglia are known to become more oscillatory and synchronized from healthy to parkinsonian conditions. Similar changes have been observed with local field potentials (LFPs). In this study, we used an unb...

Sanchez-Boccherini, J.; Gallego, C., 1981: Biologie et lutte contre Aelia rostrata en Espagne. Bulletin OEPP: 112: 43-46

Kendall, M.D., 1984: Have we underestimated the importance of the thymus in man?. Recent immunological research has concentrated on the complex and subtle interactions between T cells, B cells and accessory cells. In these studies, little attention has been given to the adult thymus gland. Modern textbooks of disease and anatom...

Mastronuzzi, T.; Paci, C.; Portincasa, P.; Montanaro, N.; Grattagliano, I., 2016: Assessing the nutritional status of older individuals in family practice: Evaluation and implications for management. Malnutrition is emerging as a multidimensional concern of ageing with a high prevalence among nursing home residents. This study investigated the extent of malnutrition among old subjects in family practice and its relationship with major complica...

Fledelius, H.; Alsbirk, P.H., 1975: Comparative ultrasound oculometry. TAU-measurements of thirty eyes with three standard equipments. Ultrasound oculometry (A mode) was performed in 30 eyes with three different standard equipments and great effort was made to make the three sets of measurements comparable. In spite of careful calibration procedures significant inter-equipment di...

Pagani, A., 1970: Fractures of the tibia. Treatment with osteosynthesis, using Allaria nails. Minerva Medica 61(91): 5215-5217

Anonymous., 1867: Uranoscopus scaber. Dr. Steindachner refers U. occidentalis Agass. and U. bufo Val. to this spec. Uranoscopus scaber. Dr. Steindachner refers U. occidentalis (Agass.) and U. bufo (Val.) to this species. Sitzgsber. Ak. Wiss. Wien, 1867, lvi, p. 695.

Jeong, S-Ho.; Lee, Y-Joon.; Park, S-Tae.; Choi, S-Kyung.; Hong, S-Chan.; Jung, E-Jung.; Ju, Y-Tae.; Jeong, C-Young.; Ha, W-Song., 2011: Synchronous Adenocarcinoma and Gastrointestinal Stromal Tumor of the Stomach Treated by a Combination of Laparoscopy-assisted Distal Gastrectomy and Wedge Resection. The simultaneous occurrence of a gastrointestinal stromal tumor (GIST) and a gastric adenocarcinoma is uncommon, and has rarely been reported in the literature. The present report describes the case of a 74-year-old male patient who initially pres...

Frumhoff, P.C., 1995: Conserving wildlife in tropical forests managed for timber. Conservationists concerned with forest biodiversity have generally focused on areas that are protected from logging, but they should also seek to preserve near-natural assemblages of plants and wildlife within tropical forests that are managed for...

Criscuolo, P.D.; Piva, L.H. de O.; Miranda, L.C.; Bortoleto, E.E.; Dulley, R.D.; Bemelmans, P.F.; Sodrzeieski, D.; Pereira, I.F., 1978: Flower production in Sao Paulo State. Part 1 - roses. The main rose producing region is the City of Sao Paulo region with 80% of the State production. Roses comprise 34% of total flower production in the State, whose value is estimated at NCr$ 426 million. The seasonal price index for roses shows its...