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Lack of relation between dopaminergic and 84 amino butyric acid ergic mechanisms in chick retina


, : Lack of relation between dopaminergic and 84 amino butyric acid ergic mechanisms in chick retina. Research Communications in Chemical Pathology & Pharmacology 40(1): 29-40

The effects of apomorphine and bromocriptine on GABA content, GAD [.alpha.-amino decarboxylase] and GABA-T [transaminase] activities in the chick retina, both in conditions of a light cycle of 12 h/day and in conditions of light deprivation for 72 h, were studies. The effects of a treatment with 2 neuroleptics, having a different action on dopamine receptors, i.e., haloperidol and sulpiride, on the same biochemical parameters were examined. Dopamine agonists and antagonists did not affect GABAergic mechanisms in the chick retina, suggesting a lack of relations between dopaminergic and GABAergic mechanisms at this level.

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