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Lack of relation between secondary hyperparathyroidism and red blood cell osmotic fragility in chronic renal failure

, : Lack of relation between secondary hyperparathyroidism and red blood cell osmotic fragility in chronic renal failure. Nephron 41(3): 241-245

The possible relationship between red blood cell (RBC) osmotic fragility and secondary hyperparathyroidism (HPT) in chronic renal failure was examined in 23 uremic patients on conservative therapy and in 42 patients on maintenance hemodialysis. Secondary HPT was evaluated by means of serum biochemistry (parathyroid hormone, calcium, phosphorus, and alkaline phosphatase) and radiographic examinations (X-ray films of the hand skeleton). This study showed increased RBC osmotic fragility in uremic patients when compared with controls, with no difference between those on conservative therapy and those on maintenance hemodialysis. No correlation between RBC osmotic fragility and the hematochemical changes associated with secondary HPT was found. No difference in RBC osmotic fragility was observed with regard to the activity (alkaline phosphatase) and the severity (X-ray findings) of secondary HPT. Effective treatment of secondary HPT by either pharmacological means (1,25-dihydroxycholecalciferol) or surgical removal was not associated with consequent improvement in RBC osmotic fragility. It is concluded that secondary HPT is probably not a major factor influencing RBC osmotic fragility in chronic renal failure.


PMID: 3840575

Other references

Gutman, A.B.; Yu, T.F., 1973: Hyperglutamatemia in primary gout. Mean plasma glutamate, estimated by column chromatography, was 80 plus or minus 27 mu mol/litre in 62 men with plasma urate values over 8.0 mg/100 ml and was 79 plus or minus 14 mu mol/litre in 12 hyperuricaemic asymptomatic sons of gouty men comp...

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Jetté, M.; Sidney, K.; Lewis, W., 1990: Fitness, performance and anthropometric characteristics of 19,185 Canadian Forces personnel classified according to body mass index. The Canadian Forces (CF), concerned with the possible adverse effects of obesity on military performance and image, recently adopted the body mass index (BMI) to monitor excess weight among its personnel. Subsequently, the records of 17,098 CF men...

Pons, L.; Nurnberger, J.; Murphy, D.; Jouvent, R.; Rips, C.; Widlocher, D., 1987: Mood-independent aberrancies of word responses and action of lithium on their repetition in manic depressed illness. Following a preceding study, two samples of patients, one French (N = 20) and one American (N = 29), from two affective disorders clinics, were given free word-association tests consisting of two successive presentations of the same list of stimul...

Tokman, M.G.; Quimby, F.W., 1994: Cytokine production during experimental toxic shock syndrome. FASEB Journal 8(4-5): A138

Wyatt, F., 1971: A clinical view of parenthood. Bulletin of the Menninger Clinic 35(3): 167-181

Anonymous, 1952: APPROVED examining boards in medical specialties: Advisory Board for Medical Specialties. Journal of the American Medical Association 150(4): 378-417

Crawford, D.C.; Heveran, C.M.; Cannon, W.Dilworth.; Foo, L.Foong.; Potter, H.G., 2009: An autologous cartilage tissue implant NeoCart for treatment of grade III chondral injury to the distal femur: prospective clinical safety trial at 2 years. The healing potential of damaged articular cartilage is limited. The NeoCart is a tissue-engineered collagen matrix seeded with autogenous chondrocytes designed for the repair of hyaline articular cartilage. The NeoCart implant is well tolerated i...

Vierbergen, G.; Heres, J.H.J.; Roosjen, M.G.; Verheul, W.J.H., 1995: A model for a pest risk assessment. Sommeijer, M J [Editor], Francke, P J [Editor] Proceedings of the Section Experimental and Applied Entomology of the Netherlands Entomological Society (N E V ) 191-192

Irving, E.L.; Sivak, J.G.; Curry, T.A.; Callender, M.G., 1996: Chick eye optics: Zero to fourteen days. Ocular dimensions and refractive state data for chicks 0 to 14 days of age were obtained from 234 untreated control eyes of birds treated unilaterally in previous work involving various defocussing lenses and/or translucent goggles. Refractive sta...