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Lack of susceptibility of marmosets saguinus mystax saguinus labiatus to human non a non b hepatitis


, : Lack of susceptibility of marmosets saguinus mystax saguinus labiatus to human non a non b hepatitis. Journal of Infectious Diseases 140(5): 794-797

Infectious sera from 3 humans with chronic non-A, non-B hepatitis whose blood or serum transmitted non-A, non-B hepatitis to other humans and to experimentally inoculated chimpanzees were inoculated into 5 marmosets. A 6th uninoculated marmoset served as a control. No elevations in levels of serum alanine aminotransferase or isocitric dehydrogenase occurred in serum samples obtained weekly from any of the marmosets during 3 mo. following inoculation. Certain marmoset species, which are susceptible to and provide well-documented animal models for hepatitis A and GB-agent hepatitis, may not be susceptible to the agent(s) of human non-A, non-B hepatitis. The agent(s) of human non-A, non-B hepatitis and the GB agent are probably different.

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