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Lactam acetals 7. synthesis and biological activities of some hetero cyclic amidines and di amidines


, : Lactam acetals 7. synthesis and biological activities of some hetero cyclic amidines and di amidines. Indian Journal of Chemistry Section B Organic Chemistry Including Medicinal Chemistry 21(9): 849-852

A variety of heterocyclic amidines and diamidines were synthesized by condensation of 1-alkyl-1-aza-2-oxocycloalkane acetals with substituted 2-aminopyridines, 2-aminopyrimidine, 2-aminobenzthiazole, 2-aminobenzimidazole, ethylenediamine, o-, m- and p-phenylenediamines and 2,3-diaminopyridine. Some of the compounds show noteworthy diuretic and antiinflammatory activities [in mice].

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