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Lactate and pyruvate levels of the anterior eye segment after uv radiation

, : Lactate and pyruvate levels of the anterior eye segment after uv radiation. Ophthalmologica 180(2): 110-118

UV keratitis was created in 2 series of rabbit eyes. Using optic-enzymatic tests pyruvate and lactate levels of the anterior eye segment were investigated after biomicroscopic controls of the damaged corneal epithelium. The lactate concentration gradient of the cornea and aqueous humor were compared with control eyes. Lactate levels of the stroma and aqueous humor of the anterior chamber were reduced significantly; the lactate:pyruvate ratio was increased in corneal epithelium and reduced in the aqueous. The direct influence of UV radiation on nucleoproteins was discussed.


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