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Lactate concentration in ventricular liquor and blood plasma after severe head injury


, : Lactate concentration in ventricular liquor and blood plasma after severe head injury. Zentralblatt fuer Neurochirurgie 46(2): 126-132

Cerebral ischemia/hypoxia is of central importance in the sequence of pathogenetic processes after severe head injuries. Investigations in 72 patients showed that after severe had injury the changes of lactate concentration in blood plasma do not allow any statement with respect to cerebral ischaemia/hypoxia. However in ventricular liquor the amount and duration of increase in lactate concentration is significantly different in nonsurvivers in comparsion to survivors. In lethal courses after 3rd day after head injury the increase of lactate concentration in ventricular liquor points to secondary cerebral ischaemia/hypoxia.

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