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Lactate dehydrogenase activity in laryngeal carcinoma and surrounding mucosa


, : Lactate dehydrogenase activity in laryngeal carcinoma and surrounding mucosa. Clinical Otolaryngology and Allied Sciences 9(1): 9-13

The total lactate dehydrogenase (LDH) activity and LDH isoenzyme pattern were measured in tissue taken from laryngeal cancers and from the laryngeal mucosa both close to and distant from the tumour margin. An increase in the total LDH activity and a cathodic shift in the isoenzyme pattern were found in tumour tissue compared to the close and distant mucosa. However, significant LDH alterations in the mucosa close to the tumour were shown in comparison to the distant mucosa and to the laryngeal mucosa of controls. Histochemical studies showed the LDH activity to be located in the basal and parabasal layers of the epithelium and in the cancer foci.

US$29.90

PMID: 6723100


Other references

Loeper, M., 1953: Oxalemia. Le Progres Medical 81(2): 39-39

Brown, D.J.; Dunlap, W.C.; Grigg, G.W.; Kelly, J., 1977: Thiazolo 5 4 d pyrimidine derivatives as amplifiers of phleomycin against escherichia coli. The acetylation of 5-amino-6-methylpyrimidine-2,4-dithione followed by cyclodehydration gave 2,7-dimethylthiazolo[5,4-d]pyrimidine-5-thione, which underwent S-alkylation by methyl iodide, 2-chloroacetamide, etc., to afford the corresponding 5-alky...

Soares, M.Britto.de.Macedo.; Moreno, R.Alberto.; Moreno, D.Hupfeld., 2002: Electroconvulsive therapy in treatment-resistant mania: case reports. Electroconvulsive therapy is known to be effective in the treatment of mood disorders, more specifically for depression and mania. Although a large body of evidence confirms the efficacy of electroconvulsive therapy in the treatment of mania, few...

Channon, J.W.; Fast, H.R.; Neil, D.A., 1972: Prairie regional studies in economic geography No.10, Rosthern region of Saskatchewan. Socio-economic activity in the Rosthern region of North-Central Saskatchewan is analyzed under five heads: (1) community attributes; (2) agricultural characteristics; (3) grain marketing; (4) implications for area of closing grain delivery points;...

Zheng, Q.X.; Xu, W.J.; Zhu, B.M.; Shen, X.R.; Kung, T.H., 1983: Purification and some properties of the nucleocapsid of wheat rosette stunt virus. Purified preparations of the nucleocapsid of WRSV were obtained by a combination of organic solvent treatment, PEG precipitation, differential centrifugation and isoelectric precipitation. Alkali hydrolysis and ribonuclease S1 digestion indicated...

Monga, M.; Pagnon, V.; Rajasekaran, M., 2001: Intracavernosal vasoactive agents induce cytotoxicity in cultured human penile cavernosal smooth muscle. Journal of Andrology (Supplement): 184, May-June

Soedjatmiko ; Handaka, 1987: Agricultural engineering technology transfer. Indonesian case. Four strategies were involved in agricultural mechanization in Indonesia. From 1950-60, large tractors and water pumps were introduced to increase food production, but by the end of the decade, no improvements had been made. 1960-70 saw a scaling...

Wearne, Ra, 1972: Rent-a-garden projects beginning to spread. Yearbook of agriculture: 10-312

Mori, H.; Mori, S.; Saitoh, Y.; Moriwaki, K.; Iida, S.; Matsumoto, K., 1985: Growth hormone-producing pituitary adenoma with crystal-like amyloid immunohistochemically positive for growth hormone. Growth hormone (GH)-producing pituitary adenoma from a 50-year-old acromegalic female was studied histochemically, immunohistochemically and electron microscopically. The adenoma was characterized by numerous crystal-like amyloid bodies of 5 to 40...

Wolff, H.; Schädlich, M.; Warnke, H.; Bohm, J.; Parsi, R.A.; Romaniuk, P.; Meyer, R.; Evers, G.; Schubel, B.; Schumacher, J., 1988: Initial clinical experiences with heart transplantation in East Germany. An account is given in this paper of first experience from orthotopic heart transplantation. Six of eight patients with transplants have so far survived, with two of these having been in very good general condition for more than a year. All surgic...