geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Lactate dehydrogenase inhibition by immunoglobulin G in human serum


, : Lactate dehydrogenase inhibition by immunoglobulin G in human serum. Clinical Chemistry 32(7): 1347-1349

Low lactate dehydrogenase (LD; EC 1.1.1.27) activity and an abnormal LD pattern in electrophoretograms of LD isoenzymes in the sera of two patients were caused by inhibition of LD by immunoglobulin G. One of these showed inhibitor activity in the serum upon direct analysis, while the other showed activity only after the immunoglobulin was stripped from the LD. As judged from the LD isoenzyme patterns in serum, the LD inhibitor appeared to act against M subunits. However, quantification of binding affinities to each isolated isoenzyme showed that the LD inhibitor had a stronger effect on LD isoenzymes 2 and 3 (H3M1 and H2M2, respectively).

US$29.90

PMID: 3719944


Other references

He, J-Rong.; Wei, D-Mei.; Chan, F-Fan.; Luan, Y-Zhu.; Tu, S.; Lu, J-Hua.; Li, W-Dong.; Yuan, M-Yang.; Chen, N-Nian.; Chen, Q-Zhu.; Lam, K.Bong.Hubert.; Cheng, K.Keung.; Xia, H-Min.; Qiu, X., 2017: Associations between maternal exposure to incense burning and blood pressure during pregnancy. Incense burning is a popular practice in Asian and Arabic countries. Previous studies show that incense burning was associated with increased risks of adverse outcomes among non-pregnant population. However, very few studies explored its health ef...

Mi, T.; Sun, S.; Zhang, G.; Carora, Y.; Du, Y.; Guo, S.; Cao, M.; Zhu, Q.; Wang, Y.; Sun, Q.; Wang, X.; Qu, C., 2016: Relationship between dyslipidemia and carotid plaques in a high-stroke-risk population in Shandong Province, China. The precise associations between stroke and carotid plaques and dyslipidemia are unclear. This population-based study aimed to examine the relationship between carotid plaques and dyslipidemia in a high-stroke-risk population. Ultrasonography of l...

Hartmann, L.F.; Portela, A.; Cardeza, A.F., 1954: Goiter or iodine uptake by thyroid after treatment with sulfur-containing compounds. Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales 148(19-20): 1653-1654

Berkey, L.G., 1967: Editorial : Trust. New York State Dental Journal 33(3): 161-162

Bolis, S.; Bregani, E.R.; Rossini, F.; Casaroli, I.; Lanzi, E.; Maffè, P.; Baldicchi, L.; Borin, L.; Mingozzi, S.; Tripputi, P., 1994: Multiple myeloma. Role of prognostic factors and staging in a therapeutic program. Patients affected with multiple myeloma constitute an heterogeneous population with very different clinical patterns, varying from asymptomatic to very compromised patients with severe and uncontrolled disease. Most common clinical and biological...

Signorelli, S.Santo.; Fiore, V.; Ruggieri, M.; Basile, A., 2015: Acute deep vein thrombosis (DVT) of the lower limbs in a 32-year-old man with chronic hypoplasia of the inferior vena cava (HIVC) without risk factors. Internal and Emergency Medicine 11(2): 273-275

Hoshinaga, K.; Shiroki, R.; Higuchi, T.; Horiba, Y.; Yanaoka, M.; Naide, Y., 1996: Quadruple immunotherapy will promise excellent graft survival in cadaveric renal transplants using cardiac arrest donor grafts. Transplantation Proceedings 28(3): 1591-1593

Yinnon, A.M.; Klutstein, M.; Balkin, J., 1988: Gonococcal endocarditis: a rare disease. Israel Journal of Medical Sciences 24(8): 429-430

Simoni R.D., 1982: Intra cellular movement of cholesterol to the plasma membrane. Federation Proceedings: Abstract 5896

Kleckner, N.; Ross, D.G., 1979: Translocation and other recombination events involving the tetracycline-resistance element Tn10. Insertions of Tn10 are characterized by the presence of a direct repetition of a 9-bp target gene sequence on either side the insertion. The occurrence of these repetitions undoubtedly reflects an important feature of the way in which DNA molecule...