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Lactate dehydrogenase isoenzymes in pleural inflammatory effusions


, : Lactate dehydrogenase isoenzymes in pleural inflammatory effusions. Jikeikai Medical Journal 31(2): 193-198

Pleural fluid lactate dehydrogenase (LDH) and LDH isoenzymes were studied in cases of pleural inflammatory effusion in pleuritis tuberculosa and pneumonia. The samples showed higher pleural fluid LDH than serum LDH with LDH isoenzyme composition of A-dominancy, i.e., LDH1 < LDH2 < LDH3 < LDH4 < LDH5. When LDH2 was dominant in isoenzyme composition, the pleural fluid LDH was lower than seurm LDH. There was a correlation between LDH level and LDH isoenzyme compositions. The higher LDH level, the more remarkable the A-subunit dominant composition. Pleural extract showed A-dominant LDH isoenzyme composition.

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