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Lactate oxidation by skeletal muscle during sustained contraction in vivo

, : Lactate oxidation by skeletal muscle during sustained contraction in vivo. Pfluegers Archiv European Journal of Physiology 366(2-3): 247-250

Estimation of lactate oxidation in vivo was carried out by a radioactive tracer technique in the muscles of the lower hindleg of the dog during tetani of different duration. The fractional (%) rate of lactate oxidation increased markedly, compared with that of the resting muscle, after the first 2 min of stimulation. Lactate oxidation afforded a large contribution to the total O2 consumption. Fatigue appeared to play a role in limiting lactate oxidation in the later phase of sustained contraction.


PMID: 1033526

DOI: 10.1007/bf00585885

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