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Modeling the isovolumic relaxation period


, : Modeling the isovolumic relaxation period. Catheterization & Cardiovascular Diagnosis 11(3): 255-268

The isovolumic relaxation period of the left ventricular pressure curve in man is assumed to be best represented by an exponential decay. To determine which model most closely approximates the empiric pressure data of isovolumic relaxation in man, several models were compared. They included linear, exponential with a zero mmHg pressure asymptote, exponential with a variable asymptote and 2nd-to 5th-order polynomials. In addition, 4 different methods of computing parameters of isovolumic relaxation by the exponential model with a variable asymptote were tested. The isovolumic relaxation period approximates an exponential, that the theoretic asymptote is variable, and that the Levenburg-Marquardt algorithm can be used efficiently to model this period.

US$19.90

PMID: 3893739

DOI: 10.1002/ccd.1810110305


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