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Nitrite test for methaqualone

, : Nitrite test for methaqualone. Forensic Science 6(3): 135-136

Methaqualone is a non-barbiturate hypnotic drug available either as Melsedin or in combination with diphenhydramine as Mandrax. Over a million prescriptions are written annually in the United Kingdom and therefore its occurrence in human accidental and suicidal poisoning is not uncommon. Details of a simple qualitative test suitable for detecting milligram quantities of methaqualone are presented. A similar reaction undergone by 2,4,6-triaminopyrimidine suggests that the mechanism involves diazotization of an intermediate product.


PMID: 1225774

DOI: 10.1016/0300-9432(75)90003-5

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