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Phagocytosis of monocytes in cancer patients

, : Phagocytosis of monocytes in cancer patients. Zeitschrift fuer Krebsforschung und Klinische Onkologie 91(1): 11-18

The phagocytic activity of monocytes directed at yeast particles was investigated in patients with untreated malignant tumors and in normal controls. Phagocytic activity was significantly increased in the patients. The increased activity was caused by factors contained in the patient's plasma. These factors were only partly destroyed by heat inactivation, suggesting that heat labile and heat stabile factors contributed to the observed enhancing effect on phagocytic activity. The heat labile portion may be the complement component C 5, while the heat stabile portion is so far undefined.


PMID: 146337

DOI: 10.1007/bf00305967

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