+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Piperacillin vs. carbenicillin in the therapy for serious infections

, : Piperacillin vs. carbenicillin in the therapy for serious infections. Archives of Internal Medicine 142(11): 2000-2005

There were 107 patients with either piperacillin (56) or carbenicillin (51) in an open randomized trial of hospitalized patients with pleuropulmonary (40), urinary tract (26), gynecologic (21), skin and soft-tissue (8), joint (5), bone (3) and miscellaneous other infections (bacterial) (4). Patients with urinary tract infections were given 150 mg/kg per day of piperacillin sodium or 200 mg/kg per day of carbenicillin sodium in divided doses every 6 h i.v. Patients with other infections were given 250 mg/kg per day of piperacillin sodium and 450 mg/kd per day of carbenicillin sodium; 53/56 (95%) patients treated with piperacillin and 45/51 (88%) patients treated with carbenicillin were cured clinically. In general, the drugs were well tolerated. There were, however, more adverse experiences in the group taking carbenicillin. Of special interest was the finding of liver function test abnormalities in 17/78 (21%) carbenicillin recipients (evaluative and nonevaluative cases). Thus, piperacillin evidently was effective and safe. It has potential for use in a great variety of infections.


PMID: 6215008

Other references

Sesan, T.E., 2003: Sustainable management of gray mold (Botrytis cinerea) on grapevine, strawberry and ornamentals. This review covers Botrytis diseases of grapevine, strawberry and ornamentals. The first section deals with the present status of taxonomy, genetics and molecular characterization, pathogenicity and epidemiology of the genus Botrytis. The second s...

Gusic, B., 2014: Treatment of injuries of the ethmofrontal region. Knjiga. Jugoslavenska Akademija Znanosti i Umjetnosti. Odjel Za Medicinske Nauke 3: 159-173

Yoshida, HO., 1973: Taractes rubescens and Taractlchthys steindachneri from Hawaiian waters. Fishery Bull US natn Ocean atmos Admn, 713: 900-902

Couteau, F.; Goodyer, W.; Zetka, M., 2004: Finding and keeping your partner during meiosis. HIM-3 is a meiosis-specific protein that localizes to the cores of chromosomes from the earliest stages of prophase I until the metaphase to anaphase I transition in Caenorhabditis elegans. him-3 mutations disrupt homolog alignment, synapsis, and...

Blond, B., 2002: 90% of people with apnea survive without knowing it. Soins. Gerontologie: 13-13

Dabrowski Z.; Junikiewicz E.; Miszta H.; Slosarczyk J.; Suchorowska L.; Wozniak H., 1981: The influence of acetylphenyl hydrazine on iron deposition in the mouse hematopoietic organs. In view of the hemolytic action of acetylphenylhydrazine (APHZ), changes in the bone marrow, particularly in the erythrocytic line, and qualitative changes in the Heinz bodies were studied in mice. The bone marrow, spleen, liver and kidneys were e...

Bellandi, F.; Leoncini, M.; Maioli, M.; Gallopin, M.; Sestini, S.; Coppola, A.; Dabizzi, R.P., 2002: Intracoronary abciximab downstream of coronary occlusion may increase myocardial salvage in acute myocardial infarction treated with primary coronary intervention. Circulation 106(19 Supplement): II-535, November 5

Harding, P.J.; Thomas, E.E., 1942: Relation of ascorbic acid concentration in juice of Florida grapefruit to variety, rootstock, and position of fruit on the tree. The ascorbic acid conc. was detd. for 390 individual grapefruits from outside and inside branches of 5 trees each of Marsh grapefruit grown on rough lemon, of Marsh grapefruit grown on sour orange, and of Foster (pink) grapefruit grown on sour ora...

Fishbaugh, K.E.; Hvidberg, C.; Byrne, S.; Herkenhoff, K.E.; Fortezzo, C.M.; Kirk, R.; Winstrup, M., 2009: The stratigraphic record in the Martian north polar layered deposits as measured by high resolution stereo topography. Abstracts of Papers Submitted to the Lunar and Planetary Science Conference 40: 1998

Lawfield, W.N., 1959: Lawns and sportsgreens. This book is intended for amateur and professional gardeners. About half of it deals with making new lawns and half with the maintenance of estab- lished or neglected ones. The amateur will find some useful tips, but there is very little of direct...