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Placental transfer of central nervous system depressants in sheep


, : Placental transfer of central nervous system depressants in sheep. European Journal of Pharmacology 37(1): 193-196

Continuous monitoring of the fetal electrocorticogram [ECoG], eye movements and heart rate [HR] in ewes during the last month of gestation showed rapid placental transfer from the mother to the fetus of phenothiazine derivatives (acepromazine maleate), short-acting barbiturates (thiopental sodium) and narcotic analgesics (meperidine). Acepromazine and thiopental partially disrupted the fetal sleep cycle by synchronization of the ECoG for 1-2 h but increased the HR for 2-3 h. The effects of meperidine were similar but lasted only 5-10 min for the ECoG and less than 0.5 h for the HR.

US$19.90

PMID: 1278240

DOI: 10.1016/0014-2999(76)90022-4


Other references

Miranda, A.I.abel S.; Conceicao, M.S.; Borrego, C.S., 1993: A contribution to the air quality impact assessment of a roadway in Lisbon The air quality model APOLO. Science of the Total Environment 134(0): 1-7

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Boyd, I.A., 1971: Specific fusimotor control of nuclear bag and nuclear chain fibres in cat muscle spindles. Journal of Physiology 214 Suppl: 30p-31p

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Gao, Q.; Yan, Y.; Lin, X.; Tang, X.; Xie, J.; Tu, J.; Xiao, S.; Jing, A., 1989: A dermatoglyphic study of three nationalities in hunan province china 1. fingerprint. This paper reports the feature of finger-print in Han, Hui and Yan Nationalities in Human (China). The mean of total finger ridge count (TFRC) in males of Yao was much higher than that of Han and Hui. Combinations of finger pattern all permit the...

Gribova Z.P.; Solntsev M.K.; Zinchenko V.A.; Postnov L.A.; Gunar L.E.; Karavaev V.A.; El'gina L.M., 1984: The effect of tordon on the light stages of wheat photosynthesis in one time and repeated annual application. First treatment with tordon results in low-temperature peak A with TA [ambient temperature] .apprx. -14.degree. and shifting peak B to low-temperature sector of thermoluminescence curves. Repeated annual treatments also increase peak C amplitude w...

Kerenyi, M.; Batai, R.; Juhasz, V.; Batai, I., 2004: Lidocaine/prilocaine cream (EMLA) has an antibacterial effect in vitro. Journal of Hospital Infection 56(1): 75-76

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Porcella, S.F.; Fitzpatrick, C.A.; Bono, J.L., 2000: Expression and immunological analysis of the plasmid-borne mlp genes of Borrelia burgdorferi strain B31. A lipoprotein gene family first identified in Borrelia burgdorferi strain 297, designated 2.9 LP and recently renamed mlp, was found on circular and linear plasmids in the genome sequence of B. burgdorferi strain B31-M1. Sequence analyses of the B...

Cokeley, Wr, 1988: Growing Restrepias. American Orchid Society bulletin 57(8): 837-841