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Plasma lipids in twins. Environmental and genetic influences


, : Plasma lipids in twins. Environmental and genetic influences. Atherosclerosis 48(3): 265-277

A study on 205 pairs of male and female twins, aged from 18 to 34 yr, showed significant heritabilities for total and high density lipoprotein [HDL] cholesterol and for triglycerides. Significant effects of shared environment were also found for total and HDL cholesterol, possibly to a greater extent in women than in men. Triglycerides showed greater variance in men but a model specifying different sized environmental and genetic parameters in the 2 sexes gave good fit; it indicates that the factors influencing plasma triglycerides are the same in men and women although the effects they produced are scaled differently. [The protective effect of HDL cholesterol in coronary heart disease is also discussed.].

US$19.90

PMID: 6685521

DOI: 10.1016/0021-9150(83)90044-8


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